Glycosides and Oligosaccharides

Following Dr. Laurens Anderson s suggestion the title of this Chapter Is expanded many compounds containing more than one sugar unit are referred to. 

---

Kobayashi, S., Miyase, T., and Noguchi, FI., Polyphenolic glycosides and oligosaccharide multiesters from the roots of Polygala dalmaisiana, J. Nat. Prod., 65, 319, 2002. 

R. R. Schmidt, New methods for the synthesis of glycosides and oligosaccharides. Are there alternatives to the Koenigs-Knorr method Angew. Chem. lnt. Ed. Engl. 25 212 (1986). 

The next ten chapters should provide the reader with state-of-the-art methods in glycoside and oligosaccharide synthesis from leading researchers in the field. 

Special cases (e.g., sialyl glycosides and oligosaccharides glycosides of macro-lide aglycones)... 

Glycoside and Oligosaccharide Synthesis with Unprotected Glycosyl Donors Based on the Remote Activation Concept... 

II. Glycoside and Oligosaccharide Synthesis Using 3-Methoxy-2-pyridyloxy (MOP) O-Unprotected Glycosyl Donors 391... 

The stimulation of the synthesis of the cellulase system of T. reesei QM 9414 by sophorose was established as shown by the results of experiments summarized in Table IV. Other than sophorose, of the glycosides and oligosaccharides tested, only lactose caused even a limited production of the enzymes of the cellulase system. Lactose is not as closely related structurally to sophorose as is, for example, the disaccharide laminaribiose it is more closely related structurally to cellobiose, which, despite being the major product of cellulose breakdown, does not promote enzyme production under the conditions of this experiment. It was noted that both intra- and extracellular constitutive enzyme levels produced by cells growing on glucose (or by resting cells without inducer, Table IV) are less than 0.5% of the fully induced levels and thus are negligible. 

New Methods for the Synthesis of Glycosides and Oligosaccharides — Are There Alternatives to the Koenigs-Knorr Method Schmidt, R. R. Angew. Chem lm Ed, Engi 1986, 25, 212. 

Finally, it should be mentioned that enzymatic syntheses of glycosides and oligosaccharides developed rapidly, having provided an additional tool for the preparation of these compounds. As further discussion of this subject is beyond the scope of this chapter, the reader is referred to overviews given elsewhere [637-640] as starting points for further reading. 

Schmidt, R R, New methods of glycoside and oligosaccharide syntheses — are there alternatives to the Koenigs-Knorr method Augew. Chem., 98, 213-236, 1986. 

---