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Glycosaminoglycan synthase enzymes

Sugar Polymer Engineering with Glycosaminoglycan Synthase Enzymes 5 to 5,000 Sugars and a Dozen Flavors... [Pg.232]

DeAngelis 50) transferred the glycosaminoglycan (GAG) synthase genes into Bacillus subtilis to produce GAG polymers. Well-defined GAG oligosaccharides were also produced using engineered variants of these enzymes. [Pg.4]

It is believed that HA is the earliest evolutional form of glycosaminoglycans. Contrary to HA, other glycosaminoglycans are synthesized in the Golgi apparatus. They covalently bond with proteins to form the proteoglycans, which further transfer into the extracellular matrix by the exocytosis mechanism [41]. Three forms of hyaluronan synthase (HASj, HAS, HAS3) are found in human and vertebrate bodies. The enzyme HAS performs slow synthesis of high molecular weight HA, the enzyme... [Pg.20]

See other pages where Glycosaminoglycan synthase enzymes is mentioned: [Pg.191]    [Pg.308]    [Pg.8]    [Pg.253]    [Pg.11]    [Pg.162]    [Pg.232]    [Pg.237]    [Pg.432]    [Pg.15]    [Pg.45]    [Pg.103]   


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