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Glycolysis steps

Further steps m glycolysis use the d glyceraldehyde 3 phosphate formed m the aldolase catalyzed cleavage reaction as a substrate Its coproduct dihydroxyacetone phosphate is not wasted however The enzyme triose phosphate isomerase converts dihydroxyacetone phosphate to d glyceraldehyde 3 phosphate which enters the glycol ysis pathway for further transformations... [Pg.1058]

In contrast with the well-known Embden-Meyerhof-Pamass glycolysis pathway for the conversion of hexose sugars to alcohol, the steps in conversion of ethanol to acetic acid remain in some doubt. Likely, ethanol is first oxidized to acetaldehyde and water (39). For further oxidation, two alternative routes are proposed more likely, hydration of the acetaldehyde gives CH2CH(OH)2, which is oxidized to acetic acid. An alternative is the Cannizzaro-type disproportionation of two molecules of acetaldehyde to one molecule of ethanol and one molecule of acetic acid. Jicetobacter... [Pg.409]

The triose phosphate isomerase reaction completes the first phase of glycolysis, each glucose that passes through being converted to two molecules of glyceraldehyde-3-phosphate. Although the last two steps of the pathway are... [Pg.620]

Fructose-6-phosphate generated in this way enters the glycolytic pathway directly in step 3, the second priming reaction. This is the principal means for channeling fructose into glycolysis in adipose tissue, which contains high levels of fructose. [Pg.634]

Bosca, L., and Corredor, C., 1984. Is phosphofrnctokinase die rate-limiting step of glycolysis Trends in Biochemical Sciences 9 372-373. [Pg.638]

Pyruvate produced by glycolysis is a significant source of acetyl-CoA for the TCA cycle. Because, in eukaryotic ceils, glycolysis occurs in the cytoplasm, whereas the TCA cycle reactions and ail subsequent steps of aerobic metabolism take place in the mitochondria, pyruvate must first enter the mitochondria to enter the TCA cycle. The oxidative decarboxylation of pyruvate to acetyl-CoA,... [Pg.644]

The complete route of gluconeogenesis is shown in Figure 23.1, side by side with the glycolytic pathway. Gluconeogenesis employs three different reactions, catalyzed by three different enzymes, for the three steps of glycolysis that are... [Pg.744]

This enzyme interconverts ribulose-5-P and ribose-5-P via an enediol intermediate (Figure 23.30). The reaction (and mechanism) is quite similar to the phosphoglucoisomerase reaction of glycolysis, which interconverts glucose-6-P and fructose-6-P. The ribose-5-P produced in this reaction is utilized in the biosynthesis of coenzymes (including N/ DH, N/ DPH, F/ D, and Big), nucleotides, and nucleic acids (DNA and RNA). The net reaction for the first four steps of the pentose phosphate pathway is... [Pg.765]

N/ JDPH is considerably greater than the need for ribose-5-phosphate. The next three steps thus return some of the five-carbon units to glyceraldehyde-3-phos-phate and fructose-6-phosphate, which can enter the glycolytic pathway. The advantage of this is that the cell has met its needs for N/VDPH and ribose-5-phosphate in a single pathway, yet at the same time it can return the excess carbon metabolites to glycolysis. [Pg.766]

The next steps of glucose catabolism are called the citric acid cycle. The pyruvic acid formed in glycolysis is transported into the mitochondria, which arc subcellular organelles with double (inner and outer) membranes. They are referred to as the powerhous-... [Pg.170]

Take glycolysis, for example, the metabolic pathway by which organisms convert glucose to pyruvate as the first step in extracting energy from carbohydrates. [Pg.903]

Glycolysis is a ten-step process that begins with isomerization of glucose from its cyclic hemiacetal form to its open-chain aldehyde form—a reverse nucleophilic addition reaction. The aldehyde then undergoes tautomerixa-tion to yield an enol, which undergoes yet another tautomerization to give the ketone fructose. [Pg.903]

Active Figure 29.7 MECHANISM The 10-step glycolysis pathway for catabolizing glucose to two molecules of pyruvate. Individual steps are described in the text. Sign in at www.thomsonedu.com to see a simulation based on this figure and to take a short quiz. [Pg.1144]

Figure 29.8 Mechanism of step 2 in glycolysis, the isomerization of glucose 6-phosphate to fructose 6-phosphate. Figure 29.8 Mechanism of step 2 in glycolysis, the isomerization of glucose 6-phosphate to fructose 6-phosphate.
Problem 29.7 Identify the two steps in glycolysis in which ATP is produced. [Pg.1150]

Step 2 of Figure 29.12 Isomerization Citrate, a prochiral tertiary alcohol, is next converted into its isomer, (2, 35)-isocitrate, a chiral secondary alcohol. The isomerization occurs in two steps, both of which are catalyzed by the same aconitase enzyme. The initial step is an ElcB dehydration of a /3-hydroxy acid to give cfs-aconitate, the same sort of reaction that occurs in step 9 of glycolysis (Figure 29.7). The second step is a conjugate nucleophilic addition of water to the C=C bond (Section 19.13). The dehydration of citrate takes place specifically on the pro-R arm—the one derived from oxaloacetate—rather than on the pro-S arm derived from acetyl CoA. [Pg.1156]


See other pages where Glycolysis steps is mentioned: [Pg.632]    [Pg.550]    [Pg.327]    [Pg.45]    [Pg.2162]    [Pg.383]    [Pg.143]    [Pg.632]    [Pg.550]    [Pg.327]    [Pg.45]    [Pg.2162]    [Pg.383]    [Pg.143]    [Pg.1114]    [Pg.1057]    [Pg.114]    [Pg.115]    [Pg.1057]    [Pg.576]    [Pg.609]    [Pg.612]    [Pg.613]    [Pg.616]    [Pg.624]    [Pg.631]    [Pg.642]    [Pg.670]    [Pg.681]    [Pg.745]    [Pg.753]    [Pg.762]    [Pg.170]    [Pg.171]    [Pg.808]    [Pg.1143]    [Pg.1147]    [Pg.1157]    [Pg.1161]    [Pg.1162]    [Pg.1163]   
See also in sourсe #XX -- [ Pg.1143 , Pg.1144 ]

See also in sourсe #XX -- [ Pg.1143 , Pg.1144 ]

See also in sourсe #XX -- [ Pg.904 ]

See also in sourсe #XX -- [ Pg.1174 ]




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Glycolysis

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