Glycerol 3-dichlorohydrin

Glycerol-<, 7-dichlorohydrin, 31, 2 Glycidic ester condensation, 34, 54 Glycine, 33, 1... 

Glycerol -dichlorohydrin, 2.3-dichloro-propanol, CH2CI CHC1 CH2 0H. Colourless liquid, b.p. 182 C. Prepared by the chlorination of propenyl alcohol. Oxidized by nitric acid to 1,2-dichloropropionic acid. Reacts with NaOH to give epichlorohydrin. 

In the reaction of aEyl alcohol with an aqueous chlorine solution, addition of hypochlorous acid to the double bond of aEyl alcohol yields glycerol monochlorohydrin and as a by-product, glycerol dichlorohydrin. Thus, a poor yield of glycerol monochlorohydrin is obtained (8). To improve the yield of glycerol monochlorohydrin, addition of sodium carbonate in an amount equivalent to that of the hydrogen chloride in the aqueous chlorine solution, has been proposed (9). 

From Allyl Ghloride. The hypochlorination of allyl chloride [107-05-1] gives a mixture of the glycerol dichlorohydrins, 2,3-dichloropropanol and 1,3-dichloropropanol about 7 3 ratio. Because of the poor solubiHty of allyl chloride in water, it is essential to minimize the formation of an organic phase in which direct chlorination of the allyl chloride results in the unwanted by-product 1,2,3-trichloropropane. 

Glutaraldehyde, gl6 Glycerol dichlorohydrin, d264 Glycerol a-monochlorohydrin, c227 Glyceryl triacetate, p200... 

The mixture is finally cooled and the ethereal solution carefully decanted from the solid, which is carefully rinsed twice with 250 cc. portions of dry ether. The united liquids are then distilled from a water bath held at 40-60°, the residue is fractionated with a column, and the fractions boiling at the following points are collected up to 110° at 110-115° at 115-117° and at 117-140°. The portion boiling at 115-117° is pure epichlorohydrin the lower and higher fractions are systematically redistilled, yielding a further quantity of pure material. The yield is 705-747 g. (76-81 per cent of the theoretical amount). The residue, varying from 16 to 150 g., consists of nearly pure glycerol dichlorohydrin, and may be employed in subsequent runs (Note 4). 

Glycerol (or Glycerin) Dichlorohydrin and Its Nitrated Derivatives. See under Dichlorohydrin and Derivatives in Vol 5 pp D1211-L to D1212-R and in Blatt, OSRD 2014(1944), as Glycerol Dichlorohydrin Nitrate... 

Glutaraldehyde, gl3 Glyceraldehyde, d398 Glycerol dichlorohydrin, d220... 

SYNS DICHLOROHYDRIN CX-DICHLOROHYDRIN sym-DICHLOROISOPROPYL ALCOHOL 1,3-DICHLOROPROPANOL-2 pOT) GLYCEROL a,J-DICHLOROHYDRIN sym-GLYCEROL DICHLOROHYDRIN U 25,354... 

Dichloro-l, 3-dideoxyglyceritol (glycerol dichlorohydrin LXII) was therefore prepared from glyceritol (VII), and oxidized to 1,3-dichloro-2-propanone (LXIII) which, upon addition of hydrogen cyanide and hydrolysis of the resulting nitrile (LXIV), gave a quantitative yield of 3-chloro-2-(chloromethyl)-2-hydroxypropanoic acid (LXV). This chloro acid (LXV)... 

The reactions of epichlorohydrin are similar to those of glycerol dichlorohydrins (Riesser 1979). Epichlorohydrin is often classified as a chlorohydrin. However, as it is a chloroether with an epoxide structure, it is discussed in Chapter 16. 

The organic dihalides most often used are those that are commercially available such as methylene chloride, ethylene dichloride, propylene di-chloride, glycerol dichlorohydrin, dichloroethyl ether, dichloroethylformal, and triglycol dichloride. The most reactive chloro-compounds are the primary ones and these are the most commonly used. 

Glycerol DIchlorohydrIn DIchloroisopropyl Alcohol l,3-DIchloropropanol-2 Ct Propeny Id I ch I orohydri n PHYSICAL PROPERTIES... 

Glycerol a,Y-dichlorohydrin sym-Glycerol dichlorohydrin 2-Propanol, 1,3-dichloro- ... 

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