Glutamate aspartate transporter protein

Tolner, B., Poolman, B., Wallace, B., and Konings, W. N. (1992) Revised nucleotide sequence of the gltP gene, which encodes the proton-glutamate-aspartate transport protein of Escherichia coli K-12. J. Bacteriol. 174, 2391-2393. 

Some of the amino acids undergo facilitated diffusion through selective transport proteins into the bloodstream, from which they are taken up by the liver and other organs. Others, particularly glutamate, glutamine, aspartate, and asparagine, are metabolized by the gut cells for energy. 

Operation of the most widespread shuttle—the malate-aspartate shuttle is depicted in Figure 8 10. Critical to the shuttle are two antiport proteins in the inner mitochondrial membrane, a malate/a-ketoglutarate antiporter and a glutamate/aspartate antiporter, that permit transport of their... 

Several symport proteins have been identified in the luminal and basolateral surfaces of the proximal tubule cells, each with a specific transport function. For example, mechanisms exist for transport of (i) neutral amino acids, except glycine, (ii) glycine alone, (iii) acidic amino acids (glutamate and aspartate), (iv) basic amino acids... 

---