Glucose tolerance effect

Vuksan V, Stavro MP, Sievenpiper JL, et al (2000) American ginseng improves glycemia in individuals with normal glucose tolerance effect of dose and time escalation. J Am Coll Nutr 19 738-744... 

Chromium. The history of the investigations estabHshing the essentiaHty of chromium has been reviewed (136). An effect of brewer s yeast in preventing or curing impaired glucose tolerance in rats was revealed, and the active factor was identified as a Cr(III) organic complex, glucose tolerance... 

Brewers and bakers dried yeasts are used as dietary supplements. They contribute some protein and trace minerals, and some B vitamins, but no vitamin C, vitamin B 2 or fat-soluble vitamins. The glucose tolerance factor (GTE) of yeast, chromium nicotinate, mediates the effect of insulin. It seems to be important for older persons who caimot synthesize GTE from inorganic dietary chromium. The ceU wall fraction of bakers yeast reduces cholesterol levels in rats fed a hypercholesteremic diet. 

DPP-4 is a serine protease that inactivates GLP-1. GLP-1 stimulates insulin secretion and suppresses glucagon release. The inhibition of DPP-4 prolongs the half-life of GLP-1 and brings about beneficial effects on glucose levels and glucose tolerance in type 2 diabetics. Backes et al. [64] report on the parallel optimization of enzyme binding affinity and inhibition, selectivity, ADME properties, and PK (Scheme 19). 

Hayashi K, Kurushima H, Kuga Y, Shingu T, Tanaka K, Yasunobu Y, et al. Comparison of the effect of bezafibrate on improvement of atherogenic lipoproteins in Japanese familial combined hy-perlipidemic patients with or without impaired glucose tolerance. Cardiovasc Drugs Ther 1998 12 3-12. 

Preston, A.M., R.P. Dowdy, M.A. Preston, and J.N. Freeman. 1976. Effect of dietary chromium on glucose tolerance and serum cholesterol in guinea pigs. Jour. Nutr. 106 1391-1397. 

Diabetic patients require more intense medical monitoring and selfmonitoring of blood glucose. Some anorectic agents have direct effects that improve glucose tolerance. 

Q73 Gl ucosamine should be used with care in patients with impaired glucose tolerance. Glucosamine may cause nausea, abdominal pain and indigestion as side-effects. 

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