Glucose-sensitive hydrogels

Mack AC, Jinshu M, McShane MJ. Transduction of pH and glucose-sensitive hydrogel swelling through fluorescence resonance energy transfer. IEEE Sensors 2005,2,912-915. 

Obaidat, A.A. and Park, K. (1997) Characterization of protein release through glucose-sensitive hydrogel membranes. Biomaterials, 18 801-807. 

Describe the approaches to the development of glucose-sensitive hydrogels. 

Kim, J.J. Park, K. 2001, Modulated insulin delivery from glucose-sensitive hydrogel dosage forms , Journal of Controlled Release, vol. 77, no. 1-2, pp. 39-47. 

Zhang, R., Tang, M., Bowyer, A., Eisenthal, R. Hubble, J. 2006, Synthesis and characterization of a D-glucose sensitive hydrogel based on CM-dextran and concanayalin A , Reactive and Functional Polymers, vol. 66, no. 7, pp. 757-767. 

Glucose-sensitive hydrogels respond to changes in glucose concentration by swelling or collapsing in a surrounding... 

Figure 4 Depiction of glucose-sensitive hydrogel. Glucose diffuses into collapsed hydrogel and binds with glucose oxidase (a). This leads to the formation of gluconic acid, which causes the pH-sensitive polymer to swell (b).

New Orleans, La., Spring 1996, p.372-3. 012 RELEASE OF INSULIN FROM GLUCOSE-SENSITIVE HYDROGELS Podual K Doyle F J Peppas N A Purdue University... 

The glucose-induced osmotic swelling pressure of the PBA-containing, glucose-sensitive hydrogel can be measured by confining it between a porous membrane and the diaphragm of a miniature pressure transducer. In this... 

Intelligent stimuli-responsive delivery systems using hydrogels that can release insulin are referred to as glucose-sensitive hydrogels and are a field of intensive research (Ehrick et al, 2009 Kim and Park, 2001 Traitel et al, 2000). One of the challenges in the controlled drug delivery area includes the... 

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