Gluconeogenesis glucose formation from non-carbohydrate sources

Gluconeogenesis glucose formation from non-carbohydrate sources [Pg.112]

The three reactions are catalysed by glucose 6-phosphate Glucose enters the blood from three different sources dehydrogenase, gluconolactonase and phosphogluconate depending on the conditions. [Pg.112]

Gluconeogenesis is the de novo synthesis of glucose from none carbohydrate sources. These sources (precursors) are lactic acid, glycerol and the amino acids, especially alanine, glntamine and aspartic acid (Fignre 6.22). [Pg.113]

Lactic acid The normal concentration of lactate in the blood is about 1 mmol/L which is the balance between production and utilisation. Various tissues produce lactic acid and release it into the blood, from where it is taken up by liver and converted to glucose (or glycogen) (the Cori cycle, see above). [Pg.113]

The glycerol 3-phosphate is oxidised by glycerol 3-phosphate dehydrogenase to produce dihydroxyacetone phosphate [Pg.113]

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