Glucocorticoid response element binding

Binds (through the zinc fingers) to the glucocorticoid response element (GRE) associ-. ated with the PEPCK gene, which... 

It has now been found that the glucocorticoid response elements of mouse mammary tumour virus and the gene for chicken lysozyme also bind progesterone re-... 

The glucocorticoid receptor enhances or represses transcription by binding to specific DNA sequences, termed glucocorticoid response elements. The protein is organized as functional domains, in an ar-... 

Cairns W, Cairns C, Pongratz I, et al. Assembly of a glucocorticoid receptor complex prior to DNA binding enhances its specific interaction with a glucocorticoid response element. J Biol Chem 1991 266 11221-6. 

GRE. (glucocorticoid response element). The glucocorticoid receptor is essentially a transA binding site in a promoter to which the activated glucocorticoid receptor can bind to a transcription factor which is activated only in the presence of glucocorticoids. The activated receptor will bind to a GRE, and transcription of the adjacent gene will be altered. See response element. 

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