Glaucoma chronic wide-angle

All of the following drugs are used topically in the treatment of chronic wide-angle glaucoma. Which of these agents reduces intraocular pressure by decreasing the formation of the aqueous humor ... 

It is nonselective agent with no local anaesthetic activity and having excellent ocular hypotensive effect preferred for ophthalmic use. It is useful in chronic wide-angle and aphakic glaucoma. Levobunolol and betaxolol are other agents used as ophthalmic preparation used in glaucoma. 

Uses treatment of chronic wide-angle glaucoma... 

Primary open-angle glaucoma is a very common form (also known as chronic simple or wide-angle glaucoma). It results from obstruction in the trabecular meshwork which acts as the drainage system for the aqueous humour. 

Relative transdermal scopolamine may cause mydriasis leading to an increase in intraocular pressure in patients with chronic open-angle (wide-angle) glaucoma and should be used with caution. Patients with known liver or kidney dysfunction should use scopolamine patch with caution. Patients with history of psychosis or seizures should also avoid transdermal scopolamine. 

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