Ibuprofen Ginkgo biloba

We do not recommend the routine use of selegiline, nonsteroidal anti-inflammatory drugs like ibuprofen, or herbs such as ginkgo biloba for patients with dementia. These all have the potential for problematic side effects that may outweigh their benefit. If they are used, please be sure that a physician closely monitors your patient. 

Clinically important, potentially hazardous interactions with acenocoumarol, anagrelide, anticoagulants, bismuth, boswellia, calcium hydroxylapatite, capsicum, cholestyramine, desvenlafaxine, devil s claw, dexamethasone, dexibuprofen, dicumarol, etodolac, evening primrose, flunisolide, ginkgo biloba, ginseng, heparin, ibuprofen, indomethacin, ketoprofen, ketorolac, lumiracoxib, methotrexate, methylprednisolone, nilutamide, NSAIDs, phellodendron, prednisone, resveratrol, reteplase, rivaroxaban, sermorelin, sulfites, tirofiban, triamcinolone, urokinase, valdecoxib, valproic acid, verapamil, warfarin... 

Meisel, C., Johne, A., and Roots, I. 2003. Fatal intracerebral mass bleeding associated with Ginkgo biloba and ibuprofen. Atherosclerosis 167, 367. 

As a general precaution, ginkgo biloba may increase the risk of excessive bleeding, especially for people with blood circulation disorders and for those taking ibuprofen, aspirin, or other anti-coagulants. 

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