Mutagenicity genotoxicity compared with

Miguel, A. H., J. M. Daisey, and J. A. Sousa, Comparative Study of the Mutagenic and Genotoxic Activity Associated with Inhalable Particulate Matter in Rio de Janeiro Air, Environ. Mol. Mutagen., 15, 36-43 (1990). 

A study of the genotoxicity of feverfew in humans examined the number of sister-chromatid exchanges in feverfew users compared with nonusers and indicated that no adverse effects of feverfew were found. The mutagenicity of urine samples from feverfew users was tested using the Ames mutagenicity test. The frequency of chromosomal aberrations was lower in the feverfew group than in the control group (Johnson et al. 1987). 

After the discovery of MVOC, these compounds were also thought to provoke certain symptoms of sick building syndrome in view of their similarity to commonly found VOC, which may cause symptoms like headache and dizziness. However, since MVOC concentrations are normally 2-3 decimal powers lower than those of comparable VOC, these low concentrations should not be expected to have any effects in indoor air [75]. Mutagenic, cytotoxic or genotoxic effects were not found in vitro in mammalian cells with typical MVOC like 2-pentylfuran, 1-butanol, 2-butanone, 3-methyl-l-butanol, 2-methyl-l-propanol, 2-hexanone, 2-heptanone, l-octen-3-ol, 3-octanone or... 

---