Genomics and Proteomics

Thongboonkerd V. Genomics, proteomics and integrative omics in hypertension research. Curr Opin Nephrol Hypertens 2005 14 133-9. 

The number of sites in the array can be used for combinatorial purposes. Combinatorial experiments can be oriented to a diversity of applications, genomics, proteomics, and biochemical, in general. Molecular inversion and SNP Genotyping are well-proven uses of the technology. 

This is a reflection of the increasing knowledge of the complexity of in viva systems, and also the current powerful computational resources to capture, analyze, interpret and model those systems. In view of this complexity, not only the development of genomics, proteomics and metabonomics databases, but also the development of systems biology methods helps us to understand the underlying mechanisms in any given ADME process [80]. 

Robertson D, Beuhausen S, Pennie W. Toxicopanomics applications of genomics, proteomics and metabonomics in predictive and mechanistic toxicology. In Hayes AW, ed. Principles and Methods of Toxicology. 5th ed. Florida CR Press, 2007. 

If this succeeds, schistosomes may be close to becoming a model for parasitic trema-todes. This would allow researchers to further develop and optimize techniques for the genetic modification of other parasitic flat-worms of medical or economic relevance. The combination of modern molecular approaches such as genomics, proteomics and transgenics, with classical disciplines such as systematics,... 

Kero, F. H., Pedder, R. E., and Yost, R. A. (2005). Quadrupole mass analyzers Theoretical and practical considerations. In Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics, Part 3 Proteomics. Wiley, Hoboken, NJ. 

This example clearly shows that with further improvement in sensitivity, online cHPLC-NMR, in conjunction with cHPLC-MS, is likely to be used as the major tool for the successful treatment of problems encountered with genomics, proteomics and drug metabolomics. 

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