Genome analysis implications

Kralovicova J, Hammarstrom L, Plebani A, Webster ADB, Vorechovsky I (2003) Fine-scale mapping at IGAD1 and genome-wide genetic lingage analysis implicate HLA-DQ/DR as a major susceptibility locus in selective IgA deficiency and common variable immunodeficiency. J Immunol, 170 2765-2775. 

Tettelin, H., Masignani, V., Cieslewicz, M.J., Donati, C. et al (2005) Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae implications for the microbial pan-genome . Proc. Natl. Acad. Sci. U.S.A., 102, 13950-13955. 

KLOSE, J., KOBALZ, U., Two-dimensional electrophoresis of proteins An updated protocol and implications for a functional analysis of the genome, Electrophoresis, 1995,16,1034-1059. 

Kell DB, Mendes P (1999) Snapshots of systems metabolic control analysis and biotechnology in the post-genomic era. In Cornish-Bowden A, Cardenas ML (eds). Technological and Medical Implications of Metabolic Control Analysis (in press) (and see http //gepasi.dbs.aber.ac.uk/dbk/mca99.htm). Plenum Press, New York... 

Since alterations in global DNA methylation are implicated in various pathobio-logical processes, a gradient IPC-ESI-MS/MS method with a volatile IPR was used to determine cytosine and 5-methylcytosine in DNA quantification relied on stable isotope dilution [58], Muscular dystrophies caused by various mutations in the dystrophin gene are amenable to easier prenatal diagnosis via a multiplex polymerase chain reaction (PCR)/IPC assay [59]. Some guidelines for the analysis of genomic DNA by IPC-ESl-MS can be found in Reference 60. 

Tebbe, A., Klein, C., Schmidt, A., Bisle, B., Konstandinidis, K., Scheffer, B., Lottspeich, F., Siedler, F., Pfeiffer, F. and Oesterhelt, D. (2005) Analysis of the cytosolic proteome of halobac-terium salinamm - implications for genome annotation and differential expression. Proceedings of the 53rd ASMS Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, June5-June9, 2005. 

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