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Genetic factors, drug response,

We have already noted evidence for genetic factors that underlie the preference for and response to caffeine. These factors create a biologically based set of individual difference dimensions that may be modified by experience with the drug. In addition, there is evidence for a number of broader individual difference dimensions that appear to be relevant. These bipolar continua differentiate between subjects who are habitually high in arousal or arousability and those who are habitually low. The factors in question are personality dimensions that theoretically reflect underlying biological continua of arousal or arousability.238 Included among these dimensions are extraversion,58 impulsivity,239240 and sensation-seek-ing.94-241-242 We will take up the first two of these. [Pg.277]

Non-genetic factors influencing drug responses dietary and sociocultural... [Pg.39]

As shown in Figure 15.1, variations in the ethnic response to drugs are related to many interlinking factors. Genetic factors that control both pharmacokinetics and... [Pg.171]

Variability and ADR in Drug Response Contribution of Genetic Factors... [Pg.59]

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See also in sourсe #XX -- [ Pg.763 ]



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Genetics factor

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