Genetic modification enzymes

It is known that many chemicals, e.g. polynuclear aromatic hydrocarbons require enzyme modification before becoming biologically active. The production of such so-called "ultimate mutagens or carcinogens" is dependent on a series of inducible enzymes. The induction of these enzymes may increase or decrease the ultimate effect of the parent molecule. These inducible enzyme systems are also under genetic control, raising the question of the existence of susceptible individuals in the general population. 

To increase their use and to fulfill the various demands for functionality of different cellulose products, they are often modified by physical, chemical, enzymic, or genetic means. Modification leads to changes in the properties and behavior of the polymer and, consequently, improvement of the positive attributes and reduction of the negative characteristics." " " " The properties of a... 

Truncated Forms. Tmncated forms of hGH have been produced, either through the actions of enzymes or by genetic methods. 2-CAP, generated by the controlled actions of the trypsin, has the first eight residues at the N-terminus of hGH removed. Other tmncated versions of hGH have been produced by modification of the gene before expression in a suitable host. The first 13 residues have been removed to yield a derivative having distinctive biological properties (30). In this latter case the polypeptide chain is not cleaved. 

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