Geneseq database

Whereas most patent sequences are available in the public domain for use in research and for commercial exdoitation, there is a substantial body that are the subject of patent protection. It is often useful when conducting searches of sequence databases to be aware of the sequences that are patented because this may imply certain restrictions on the use to which these sequences can be put in a commercial context. The commercial repository is maintained by Derwent (Thomson Scientific), which generates the Geneseq database of patented sequences. This is a useful collectionbe-cause it contains a broad historical collection as well as more recent examples, although the terms for a commercial license to use the database may be off-putting to some potential users. There are also patent sections of Gen-Bank/EMBL DNA databases too. but these are of limited value because they contain only more recent sequence data. 

Nucleic acid and protein sequence analysis, including secondary structure prediction. GenBank, EMBL, SWISS-PROT, PIR, PROSITE, NASITE, and Vector-Bank databases on CD-ROM. Macintosh. PC/GENE for sequence analysis on PCs. IntelliGenetics Suite Sequence Analysis Software and GENESEQ database with patented protein and nucleic acid sequences. Sun and VAX. 

Besides the worldwide WPI database, Derwent provides on the ORBIT system the USPatents database, a bibhographic file of patent front page and cl aim information for U.S. patents since 1971. Derwent also produces a biotechnology database, GENESEQ, that indexes sequence stmetures of proteins or nucleic acids disclosed specifically or genetically in patents. This database is searchable with special sequence software on the InteUiGenetics system, and is a new addition to STN s database catalog. 

GeneSeq . Thomson Derwent s biosequence database, provides information on nucleic and amino acid sequences found in the patent literature. It has biosequence indexing for the patents included in the DWPI database beginning with the very first patents to carry protein and nucleotide sequence descriptions. GeneSeq structure searches retrieve records with the sequence, a short abstract directed to that sequence. 

Austin R, Ridley D. Information Resomces for Biotechnologists, Part 1 Sequences. ChemAust 2002 6(7) 4-12. A comparison of the coverage and completeness of biosequence data in the major databases, GenBank, GeneSeq, and the CAS Registry File. 

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