Genes lipase

Gene activated Lipoprotein lipase fatty acid transporter protein adipocyte fatty acid binding protein acyl-CoA synthetase malic enzyme GLUT-4 glucose transporter phosphoenolpyruvate carboxykinase... 

A gene (erstEl) encoding a thermostable esterase was isolated from Escherichia coli cells that had been transformed by DNA libraries with metagenomes from environmental samples isolated from thermal habitats. The enzyme belonged to the hormone-sensitive lipase family, could be overexpressed in E. coli, was active between 30 and 95°C, and used 4-nitrophenyl esters with chain lengths of C4-C16 (Rhee et al. 2005). 

Strain Gene Length (bp) Protein Mr (mature protein) Lipase- box Type of linker region3 No and type of polymer binding domainb Reference Accession No... 

Bruschke AV et al. The Asp9 Asn mutation in the lipoprotein lipase gene is associated with increased progression of coronary atherosclerosis. Circulation 1996 94 1913-1918. 

A common hepatic lipase gene promoter variant determines clinical response to intensive lipid lowering treatment. Atherosclerosis 2000 151 266. 

Mitchell RJ, Earl L, Bray P, Fripp YJ, Williams J. DNA polymorphisms at the lipoprotein lipase gene and their association with quantitative variation in plasma high-density lipoproteins and triacylglycerides. Human Biology 1994 66 38397. 

Brocca, S., Schmidt-Dannert, C., Lotti, M., Alberghina, L. and Schmid, R.D., Design, total synthesis, and functional overexpression of the Candida rugosa lipl gene coding for a major industrial lipase. Protein Sci., 1998, 7, 1415-1422. 

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