Genentech, Inc

ARTHUR E. HUMPHREY Chairman), Lehigh University KENNETH B. BISCHOFF, University of Delaware CHARLES BOTTOMLEY, E.I. du Pont de Nemours and Company, Inc. STUART E. BUILDER, Genentech, Inc. 

Brownawell, D., Exxon Chemical Company Builder, S. E., Genentech, Inc. 

The first large-scale process to circumvent these limitations was one developed by Genentech, Inc. (South San Francisco, CA) for production of recombinant tissue plasminogen activator (tPA). This protein dissolves blood clots and can be used to treat heart attacks and strokes. This process was developed in the mid-1980s, resulting in final product licensure in 1987. The process required both regulatory and technical breakthroughs. 

Yung-Hsiang Kao Genentech, Inc., South San Francisco, California... 

Stephen Tuck Dynavax Technologies, Berkeley, California Martin Vanderlaan Genentech, Inc., South San Francisco, California Tim Wehr Bio-Rad Laboratories, Hercules, California Ping Wong Genentech, Inc., South San Francisco, California Mingde Zhu Bio-Rad Laboratories, Hercules, California... 

Chantal Felten Quality Control Analytical Technologies, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA... 

Chernausek, S.D., K.M. Attie, J.F Cara, R.G. Rosenfeld, and J. Frane, Growth hormone therapy of Turner syndrome the impact of age of estrogen replacement on final height. Genentech, Inc., Collaborative Study Group. J Clin Endocrinol Metab, 2000. 85(7) 2439-45. 

Manufacturer Eli Lilly, Indianapolis, IN Humatrope) Pharmacia, Stockholm, Sweden Genotropin) Novo Nordisk A/S, Denmark Norditropin) Genentech, Inc., South San Francisco, CA Nutropin) Serono Laboratories, Inc., Randolph, MA Saizen, Serostim)... 

Genentech, Inc. was founded in by venture capitalist Robert A. Swanson and biochemist Dr. Heibert W. Boyer. In the early 1970s, Boyer and geneticist Stanley Colien pioneered a new scientific field called recombinant DNA technology. 

Genentech, Inc., repotted the production of the first human protein manufactured in a bacteria somatostatin, a human growth hormone-releasing inhibitory factor. For the first time, a synthetic, recombinant gene was used to clone a protein. Many consider this to be the advent of the Age of Biotechnology. 

Genentech, Inc. and The City of Hope National Medical Center announced the successful laboratory production of human insulin using recombinant DNA technology. 

Immunex Corporation and Genentech, Inc. join forces to develop TRAIL/Apo2L in cancer. 

Green, J.D. 1994. Pharmaco-toxicological expert report Pulmozyme rhDNase Genentech, Inc. Hum. Exp. Toxicol. 13 Suppl 1 S1—S42. 

Biogen Idee Inc. and Genentech Inc. 2005. Rituxan prescribing information. 

Examples of specialized molecular therapeutics that have been developed from discoveries made using expression profiling experiments include chimeric human/murine antibodies for the treatment of various cancers. Ritux-imab (Rituxan Genentech Inc. South San Francisco, CA), an anti-CD20 antibody in use since 1997, was the first chimeric monoclonal antibody to... 

J. D. Green. Pbarmaco-toxicological expert report. Pulmozyme3 rtiDNase Genentech, Inc. Hum. Exp. Ibxicol 7J SI-42 (1994). 

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