Genes defined

S., and Hill, R. E. (1991). The msh-like homeobox genes define domains in the developing vertebrate eye. Development 112 1053-1061. 

Gap genes—define four broad regions in the egg hunchback (hb)... 

Pair-rule genes—define seven bands runt (runt) hairy (h) fushi tarazu (ftz) even skipped (eve ) paired (prd) odd paired (opa)... 

Segment-polarity genes—define 14 bands engrailed (en) wingless (wg) gooseberry (gb)... 

Ferguson GD, Chen XN, Korenberg JR, Herschman HR. 2000b. The human synaptotagmin IV gene defines an evolutionary break point between syntenic mouse and human chromosome regions but retains ligand inducibility and tissue specificity. J Biol Chem 275(47) 36920-36926. 

Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity 12(6), 721-727. 

Before getting to a discussion of how these things play into structure, we just want to make two final points in our comparison of the microstructure of polypeptides and synthetic polymers. First, protein chains are linear and branching is not observed. (Some polysaccharides are branched, however.) Second, proteins (as opposed to synthetic polypeptides) are monodisperse, as the DNA of the cell s genes defines the number of amino acids and their order in a chain. Even... 

Henkel, G., Weiss, D.L., McCoy, R, Deloughery, T., Tara, D. and Brown, M.A. (1992). A DNase I-hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer. J. Immunol. 149, 3239-3946. 

Sutcliffe JS, Nakao M, Christian S, Orstavik KH, Tommerup N, Ledbetter DH, et al. Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region. Nature Genet 1994 8 52-8. 

Aroian, R.V. Lesa, G.M. Sternberg, P.W. Mutations in the Caenorhabditis elegans let-23 EGFR-like gene define elements important for cell-type specificity and function. EMBO J., 13, 360-366 (1994)... 

Smith, W. C., McKendry, R., Ribisi, S. J., and Harland, R. M. (1995) A nodal-related gene defines a physical and functional domain within the Spemann organizer. Cell 82, 37 46. 

Seppala R, Lehto VP, Gahl WA. Mutations in the human UDP-N-acetylglucosamine 2-epimerase gene define the disease sialuria and the allosteric site of the enzyme. Am J Hum Genet 1999 64(6) 1563. 

D.A. Liebermann, A.J. Fomace jr.. The gadd and Myd genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth. Mol Cell. Biol. 14 2361-2371... 

The program of viral gene expression that defines a productive infection has been subject to intense scrutiny, but will be described only briefly here the interested reader is referred to Tooze (1980), Ziff (1980), or Flint (1982) for more detailed information. Early genes, defined as those expressed prior to the onset of viral DNA replication, are expressed as six transcriptional units ElA, ElB, E2, E3, E4,... 

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