Gastrointestinal tract caustic materials

Swallowing. If it is sufficiently irritant or caustic, a swallowed material may cause local effects on the mouth, pharynx, esophagus, and stomach. Additionally, carcinogenic materials may induce tumor formation in the alimentary tract. Also, the gastrointestinal tract is an important route by which toxic materials are absorbed. The sites of absorption and factors regulating absorption have been reviewed (42,43). 

SAFETY PROFILE Poison by ingestion and intraperitoneal routes. A caustic material which is a severe eye, skin, and mucous membrane irritant. Experimental reproductive effects. Ingestion causes gastrointestinal tract upset. Violent reaction with p2. When heated to decomposition it emits toxic fumes of Na20. Used in cosmetics. See also SILICATES. 

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