Gastrointestinal syndrome

In the U.S., the central nervous system syndrome is usually more common among children, and the gastrointestinal syndrome is more prevalent in adults. Exposure to lead is also linked to decreased fertility in men. Lead is a probable human carcinogen, based on sufficient animal evidence. Populations at increased risk of toxicity from exposure to lead include developing fetuses and young children, individuals with decreased kidney function, and children with sickle-cell anemia. 

Gastrointestinal Syndrome Illness resulting from acute exposure to a chemical or ionizing radiation, resulting in damage to the gastrointestinal tract. 

In 25 adults, aged 18-40 years, three different patterns of symptoms led to hospitalization muscle weakness (n = 9), gastrointestinal complaints, including abdominal pain and hematemesis (n = 6), and neuropsychiatric disorders, including altered mental status, cerebellar abnormalities, and peripheral neuropathy (n = 10) (5). Hypokalemia (n = 13), hypophosphatemia (n = 10), hyperchloremia (n = 22), and hypobicarbonatemia (n = 23) were common. There was rhabdomyolysis in 10 patients. The muscle weakness and gastrointestinal syndromes resolved within 1-3 days of abstinence from sniffing and repletion of fluid and electrolytes. 

Exposure to 1,000 rad (10 Gy) or more will lead to gastrointestinal syndrome and, most likely, death within 3 to 10 days of exposure. Radiation exposure in this range sterilizes dividing crypt cells, leading to loss of cells from the villi. Within a few days, the villi become almost totally flat as the outer surface sloughs off and... 

Treatment for patients suffering from gastrointestinal syndrome include antiemetics, sedatives, a bland diet, and fluid replacement. Antibiotic treatment and blood transfusions are sometimes helpful in keeping patients alive through the first few days or weeks. 

Main gastrointestinal syndrome vomiting, diarrheas, sometimes stomach pain. 

In addition, the documented radioprotectant activity of Cu(II)(3,5-DIPS)2 [505] is consistent with its anti-inflammatory activity [22, 84, 514], which relates to protection against the hematopoietic syndrome, its antiulcer activity [22, 84, 91, 514-516], which relates to its potential ability to protect against the gastrointestinal syndrome, and its anticonvulsant activity [324, 326, 516], which relates to its potential to protect against the central nervous system syndrome. 

Moore, J.V. 1986. The gastrointestinal syndrome after chemotherapy inferences from mouse survival time, and from histo-logicaUy-and clonogenically-defmed cell death in intestinal crypts. Br J Cancer, Supplement 7 16. 

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