Gastrin family hormones

Potential Bioactive Conformations of Hormones of the Gastrin Family... 

Gastrin family, a member of the gastroen-teropancreatic peptide families. This family comprises the mammalian hormones gastrin and cholecystokinin, the pro-tochordean neuropeptide cionin, and... 

Growth-Arrest-Specific protein 2 Domain Gastrin/cholecystokinin/caerulein family Dynamin GTPase effector domain Gelsolin homology domain G protein y subunit-like motifs Glycoprotein hormone a chain homologs... 

Jn Figure 2.1U, examine the order of ainiriD adds at the C termiivi of gastrin and cholecystokin. How many amino acids are identical in the two hormones Are any other identical sequences shared by these hormones Ihcsc questions are relevant lo the concept that a number of hormones with different functions are actually part of the same family of hormones. A number of proteins, such as various enzymes, hormone receptor proteins, and DNA-binding protcirLS, also share similar primary sequences and thus may becortsidered members of specific families of proteins. 

ATPase. Annu. Rev. Pharmacol. Toxicol.. 35.277-305. gastrin is the name of members of a family of peptide hormones secreted in the neuroendocrine ceils of the mucosa of the stomach, and secreted into the portal blood. 

Using peptides of the gastrin hormone family as model antigens these uncontrolled effects were fully confirmed in our laboratory (48,52). In fact, gastrin/BSA conjugates prepared in conventional manner by the water-soluble carbodiimide led in animal-dependent manner to antibodies of differentiated specificity in full agreement with results from other laboratories where immunization experiments were usually performed on a larger number of animals to obtain in a "trial and error" manner antisera of the desired specificity (53-55). 

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