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Galectins ligands

M. Huflejt, U.J. Nilsson, H. Leffler, Fluorescence polarization as an analytical tool to evaluate galectin-ligand interactions, Anal. Biochem. 2004, 334, 36-47. [Pg.660]

Ohannesian, D.W., et al. 1994. Concomitant increases in galectin-1 and its glycoconjugate ligands (carcinoembryonic antigen, lamp-1, and lamp-2) in cultured human colon carcinoma cells by sodium butyrate. Cancer Res 54 5992. [Pg.83]

Scheme 2. Ligands used for the selective inhibition of galectin-3. Scheme 2. Ligands used for the selective inhibition of galectin-3.
Putative recognition of 4-position hydroxyl of yv-acetyl-lactosamine through hydrogen-bonding interactions observed in the X-ray structure of galectin-1 from bovine spleen. (PDB entry Isit [12]). Other protein-ligand contacts are omitted for clarity... [Pg.2486]

B. Kahl-Knutsson, H. Leffler, J.M. Rini, U.J. Nilsson, Structural and thermodynamic studies on cation-II interactions in lectin-ligand complexes high-affinity galectin-3 inhibitors through fine-tuning of an ariginine-arene interaction, J. Am. Chem. Soc. 2005, 127,1737-1743. [Pg.661]

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See also in sourсe #XX -- [ Pg.639 ]



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Galectins

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