Galactosyltransferase uridine diphosphate-galactose

Uridine diphosphate galactose lactosylceramide galactosyltransferase activity in cultured normal and familial hypercholesterolemic human fibroblasts... 

Under appropriate experimental conditions, the blood type of red blood cells can be changed by addition or removal of specific carbohydrate residues. For example, when type O red blood cells are incubated with the galactose donor substrate (uridine diphosphate galactose) and the specific a-galactosyltransferase enzyme, they are... 

H14. Helting, T., Biosynthesis of heparin. Solubilisation, partial separation, and purification of uridine diphosphate-galactose acceptor galactosyltransferases from mouse mastocytoma.. Biol. Chem. 246, 815-822 (1971). 

Fig. 2. Reactions catalyzed by galactosyltransferase (GT). (a) The incorporation of galactose (Gal) into a (1—>4) linkage with JV-acelylglucosamine (NAG) to form N-acetyl-lactosamine (NAL). UDP, Uridine diphosphate, (b) Modification of the activity of GT by a-lactalbumin (a-LA) to convert it to a lactose synthase catalyzing the formation of lactose from UDP-Gal and glucose.

Schachter, H., McGuire, E. J., and Roseman, S., 1971, Sialic acids XIII. A uridine diphosphate D-galactose mucin galactosyltransferase from porcine submaxillary gland, J. Biol. Chem. 246 5321-5328. 

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