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GabaA subtypes

Benzodiazepines. Figure 3 Dissection of benzodiazepine pharmacology. The functional roles of GABAa receptor subtypes, mediating particular actions of diazepam, are indicated. A sign indicates that the respective response is mediated by the respective receptor subtype, a sign indicates that the respective response is apparently not mediated by the respective receptor subtype. ND = not determined. [Pg.253]

McKernan RM, Rosahl TW, Reynolds DS et al (2000) Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAa receptor al subtype. Nat Neurosci 3 587-592... [Pg.254]

Tobler I, Kopp C, Deboer T et al (2001) Diazepam-induced changes in sleep role of the al GABAa receptor subtype. Proc Natl Acad Sci USA 98 6464 6469... [Pg.254]

Rudolph U, Crestani F, Mohler H (2001) GABAA recpetor subtypes dissecting their pharmacological functions. Trends Pharmacol Sci 22 188-194... [Pg.519]

McKernan RM, Whiting PJ (1996) Which GABAa-receptor subtypes really occur in the brain Trends Neurosci 19 139-143... [Pg.1138]

J, Cook, G, Ferris, P, Garrett, L, Bristow, F, Marshall, G, Macaulay, A, Brown, N, Howell, O, Moore, KW, Carling, RW, Street, LJ, Castro, JF, Ragan, Cl, Dawson, GR and Whiting, PJ (2000) Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAa receptor alphal subtype. Nat. Neurosci. 3 587-592. [Pg.249]

Sur, C, Wafford, KA, Reynolds, DS, Hadingham, KL, Bromidge, F, Macaulay, A, Collinson, N, O Meara, G, Howell, O, Newman, R, Myers, J, Atack, JR, Dawson, GR, McKeman, RM, Whiting, PJ and Rosahl TW (2001) Loss of the major GABAa receptor subtype in the brain is not lethal in mice. J. Neurosci. 21 3409-3418. [Pg.250]

Rudolph, U., Crestani, F., and Mohler, H., GABAa receptor subtypes dissecting their pharmacological functions. Trends Pharmacol. Sci., 22, 188-194, 2001. [Pg.129]

GABAa receptors are chloride channels and members of a superfamily of ligand-gated ion channel receptors 293 A family of pentameric GABAA-receptor protein subtypes exists 294 The GABAa receptor is the major molecular target for the action of many drugs in the brain 296... [Pg.291]

Neuro steroids, which may be physiological modulators of brain activity, enhance GABAa receptor function 297 The three-dimensional structures of ligand-gated ion channel receptors are being modeled successfully 297 Mouse genetics reveal important functions for GABAa receptor subtypes 297... [Pg.291]

TABLE 16-1 Summary of native GABAa receptor subtypes ... [Pg.295]

Barnard, E. A, Skolnick, P., Olsen, R. W. et al. Subtypes of GABAa receptors classification on the basis of subunit structure and receptor function. Int. Union Pharmacol. XV. Pharmacol. Rev. 50 291-313,1998. [Pg.300]

Sieghart, W. and Sperk, G. Subunit composition, distribution, and function of GABAa receptor subtypes. Curr. Top. Med. Chem. 2 795-816,2002. [Pg.300]

See other pages where GabaA subtypes is mentioned: [Pg.64]    [Pg.67]    [Pg.140]    [Pg.211]    [Pg.64]    [Pg.539]    [Pg.924]    [Pg.64]    [Pg.67]    [Pg.140]    [Pg.211]    [Pg.64]    [Pg.539]    [Pg.924]    [Pg.253]    [Pg.484]    [Pg.516]    [Pg.517]    [Pg.517]    [Pg.518]    [Pg.518]    [Pg.534]    [Pg.536]    [Pg.853]    [Pg.1136]    [Pg.1137]    [Pg.405]    [Pg.114]    [Pg.114]    [Pg.296]    [Pg.22]    [Pg.445]    [Pg.294]    [Pg.297]    [Pg.299]    [Pg.565]    [Pg.631]    [Pg.35]    [Pg.85]    [Pg.86]    [Pg.87]    [Pg.87]    [Pg.88]   
See also in sourсe #XX -- [ Pg.86 , Pg.96 , Pg.97 , Pg.99 , Pg.100 ]



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GABAa receptors, activation subtypes

GabaA

Subtype

Subtypes

Subtyping

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