Fungicides, undecylenic acid

Undecylenic acid monoethanolamide, if fungicidal properties are desired... 

Undecylenic acid is a naturally occurring fungicide derived from castor oil. 

Undecylenic acid is one of the better fatty acids for use as a fungicide, although cure rates are low. It can be used in concentrations up to 10% in solutions, ointments, powders, and emulsions for topical administration. The preparation should never be applied to mucous membranes because it is a. severe irritant. Undecylenic acid has been one of the agents traditionally used for athlete s foot (tinea pedis). Cure rates are low. however. 

Lamepon UD Protein undecylenic acid condensate, potass, salt (Potassium Undecylenoyl Hydrolyzed Collagen) 31.5-32.5 In combination with active agents to support anti-dandruff action through mild fungicidal effect of the undecylenic acid... 

The antimicrobial activity of undecylenic acid is widely restricted to the inhibition of moulds including pathogenic fungi. The pH optimum is in the acidic range (4 5-6). Nevertheless undecylenic acid is listed among the preservatives allowed for the protection of cosmetics in the EC (maximum authorized concentration 0 2%). Undecylenic acid may also be applied in dermatics as a fungicide (addition rates 2-10%). For preservation purposes it is recommended to use undecylenic acid only in combination with bactericides to complete the spectrum of effectiveness. 

Fatty acid ethanolamides and isopropanolamides are solid or waxy products insoluble in water. Diethanolamides are usually pastes or liquids and show better dispersibility in water. In institutional and household formulations, shampoos, bath and shower preparations, fatty alkanolamides play the role of foam stabiliser, thickener, corrosion inhibitor, and ancillary agent that improves the skin compatibility of anionic surfactants. Undecylenic ethanolamide and undecylenic diethanolamide act as fungicides also [47]. Use of diethanolamine derivatives has legislative limitations today in some countries (but not its amides) because they are proved to be precursors of carcinogenic nitrosoamines. The probability of the nitrosoamine formation is assumed to increase in the presence of formaldehyde and formaldehyde-releasing preservatives [44-46]. 

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