Functions oogenesis

Follicle bioassay (mouse) FBA Ovarian function Oogenesis polar body oocytes on day 13 upon ovulatory stimulus Folliculogenesis and oogenesis... 

Paules, R. S., Buccione, R., Moschel, R. C., Vande Woude, G. F., and Eppig, J. J. (1989). Mouse Mos protooncogene product is present and functions during oogenesis. Proc. Natl. Acad. Sci. USA 86 5395-5399. 

In a broad sense, a major function of Vg is to invest growing oocytes with nutrients essential for developing embryos. However, the recent discovery of multiple teleost Vgs whose yolk protein products have different proteolytic fates during oogenesis led us to explore potential differences among these proteins with respect to physiological function. 

Baum JS, Arama E, Steller H, McCall K. The drosophila caspase strica and drone function redundantly in programmed cell death during oogenesis. Cell Death Differ. 2007 14 1508-17. 

While not yet conclusive, studies on the gray crescent described above may provide yet another example of substances accumulated within the GV during oogenesis which become effective only after dispersal into the cytoplasm. It would be most significant if these or other nuclear products could be related to the cytoplasmic localizations referred to earlier. Whether any of the examples yet discussed falls into this category remains to be seen and will depend to a large- extent on continued attempts to identify the nature of the active materials and their mode of action. This alone requires continued interest in the period of maturation. However, it is possible that the various factors described above are involved in more generalized metabolic functions which, while necessary to normal development, are not directly involved in the differentiation of specific cell types. 

Later experiments provided the initial evidence to suggest that the synthetic passivity of the ribosomes of unfertilized oocytes could be due to absence of interaction between templates of protein synthesis and mRNA molecules, or to the presence of too few templates, as a result of which the ribosomes were uncharged and did not form polysomes (Nemer, 1962 Wilt and Hultin, 1962 Nemer and Bard, 1963 Hultin, 1964). When synthetic systems were created in vitro and mRNA molecules were replaced by synthetic polynucleotides, no significant differences were found between the ribosomes of fertilized and unfertilized oocytes. It was soon shown, however, that the messenger RNA synthesized during oogenesis can combine with ribosomes, but cannot exercise its functions because of special protein membranes, which evidently break up during activation of the oocytes as a result of increased protease activity (Monroy et al., 1965). 

Chemical and morphological differentiation of the cytoplasm of the oocyte commences during oogenesis, in the course of growth and maturation of the oocyte, i.e., it is an active morphogenetic process. It is during this period that a special functional form of chromosomes (lamp brush type) appears, to control this differentiation. Various axes of symmetry appear in the oocytes. 

---