Functional methodology: general methods

As previously alluded to, functional methodology is not, as yet, fully standardized. The literature is bulging with methods, many times improvised on the spur of the moment to fit the needs and instruments of the researcher, with inadequate preliminary examination or statistical evaluation. This section will attempt to organize a general system of methodology for protein food products. In it, a general plan of assays will be followed by criteria for choice of assay, characteristics of Model Tests, and, finally, characteristics of Utility Tests. 

Protein Functional Methodology - Outline of General Methods... 

The general two-step anionic ftmctionalization/hydrosila-tion methodology described herein has been shown to be applicable for the preparation of a wide variety of chain-end functional groups. This method couples the quantitative silyl hydride functionalization of well-defined polymeric organo-lithium compounds using dimethylchlorosilane with the second hydrosilation step in which the silyl hydride-functionalized polymer is added to a functionalized alkene in the presence of a platinum catalyst. Although it is a... 

The thermal decomposition of acyl azides into isocyanate intermediates is known as Curtius rearrangement reaction (Scheme 5.2) [27, 28]. Conventionally used general methods to synthesize aroyl azides are limited to diazotization of hydrazides and reactions of NaNs with acid chlorides, mixed anhydrides, and Al-acyl benzotriazoles [35-38]. However, these procedures involve highly reactive chemicals which put significant limitations on functionalities of the substrate. The development of methodologically new, highly functional-group tolerant, catalytic routes to aroyl azides is particularly desirable. 

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