From Punica granatum Punicaceae

The simple piperidine pelletierine from Punica granatum (pomegranate) (Punicaceae) and Duboisia myoporoides (Solanaceae) is an anthelmintic. The simple piperidine derivatives deoxy-mannojirimycin (DMJ) and deoxynojirimycin (DNJ) from Lonchocarpus species (Fabaceae) are glycosidase inhibitors because they are structurally similar to the pyranose (six-membered ring) sugar moieties of the glycosidase disaccharide substrates. 

The simple piperidine alkaloids, pelletierine, isopelletierine, A/-methylpelletierine, and pseudopelletierine, were isolated (106, 108) from the root bark of Punica granatum (Punicaceae), which had been used as an anthelmintic. Later, it was found that (-)-pelletierine possessed the i -configuration, and isopelletierine was racemic pelletierine (12, 51). 

The first phytooestrogen identified in plants was oestrone, found in small quantities in pahn and pahn kernel oils (obtained from oil pahn, Elaeis guineensis, Arecaceae) and pomegranate seeds Punica granatum, Punicaceae). 

The fruits of pomegranate (Punica granatum, L. Punicaceae) are popular in the East and far East countries. The dried pericarp has been utilized in folk medicine for colic, colitis, diarrhea, dysentery, leucorrhea, menorrhagia, oxyuriasis, paralysis and rectocele. The flavonoid extract from cold pressed seed oil showed 31-44% inhibition of sheep COX-1 enzyme and 69-81% inhibition of soybean lipoxygenase [181]. 

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