Free radicals anthocyanin scavenging

Cyanidin inhibits epidermal growth factor receptor tyrosine kinase (EGF-RTK), a-glycosidase and COX-1 and COX-2. Delphinidin (3,5,7,3, 4, 5 -hexahydroxyflavylium) also inhibits EGF-RTK. Anthocyanidins and anthocyanins can be anti-inflammatory antioxidants by acting as free radical scavengers. Thus, nasunin (delphinidin-3-(j6-coumaroylrutinoside)-5-glucoside) scavenges OH (hydroxyl), 02 (superoxide) and lipid peroxyl radicals and inhibits lipid peroxidation. 

Saint-Cricq de Gaulejac, N., Glories, Y., and Vivas, N. 1999. Free radical scavenging effect of anthocyanins in red wines. Food Res. Int. 32 327-333. 

The anthocyanin pigments of bilberries Vaccinium myrtillus have long been used to treat circulatory disorders and improve visual acuity [39]. There is experimental evidence that certain flavonoids and anthocyanins have anti-inflammatoiy properties. Orally administered anthocyanins are beneficial for treating ulcers and diabetes, and they may have antimicrobial and antiviral activities. The chemical evidence for these flavonoid properties is believed to be related to their antioxidant capacity, which is their ability to scavenge and trap free radicals that damage biomolecules [42]. 

In a study of different free radical scavenging systems, it was observed that the jambolan skin had significant antioxidant activity, which was attributed in part to antioxidant vitamins, phenolics or tannins, and anthocyanins (Baneijee etal., 2005). 

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