Fragile drugs

Table 1 Advantages and disadvantages of hydrogels as tissue engineering matrices Advantages Aqueous environment can protect cells and fragile drugs (peptides,...

Abdel-Rahman MS, Scatina J. 1985. The effect of Alcide , a new antimicrobial drug, on rat blood glutathione and erythrocyte osmotic fragility, in vitro. J Appl Toxicol 5(3) 178-181. 

The situation, while stable, is fragile and could be undone by any number of factors. More importantly, since there are still 25 million problem drug users in the world, there is plenty of room for improvement. 

Methylesculetol-6,7-dinicotinate (32) is useful as an antiinflammatory and vasodilator oflow toxicity (101). The synthesis of asarone [5555-15-1] (2,4,5-trimethoxy-l-propenylbenzene), which is used as a tranquilizer, has been patented (102). It occurs in calamus root, Acorns calamus L.y and is a chemosterilant for insects (103). 6,7-Dihydroxycoumarin-4-methylsulfonic acid and its salts are useful in the treatment of capillary permeability and fragility and for protecting oxidizable metabolites and drugs against biooxidation (104). Certain chromones derived from hydroxyhydroquinone, eg (33), and its salts, esters, and amides are valuable in the prophylactic treatment of asthma (105) (see Antiasthmatic agents). 2-Methoxy-6-multiprenyl-l,4-benzoquinones are intermediates in the microbiological synthesis of coenzyme Q compounds (106). 

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