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Foscarnet sodium phosphonoformate

R. P. Iyer, J. H. Boal, L. R. Phillips, D. R. Thakker, W. Egan, Synthesis, Hydrolytic Behavior, and Anti-HIV Activity of Selected Acyloxyalkyl Esters of Trisodium Phosphonoformate (Foscarnet Sodium) , J. Pharm. Sci. 1994, 83, 1269- 1273. [Pg.604]

Common Name Foscarnet sodium Foscarnetum natricum Trisodium phosphonoformate... [Pg.1711]

Iyer, R.P., Phillips, L.R., Biddle, J.A., Thakker, D.R., Egan, W., Aoki, S., and Mitsuya, H., Synthesis of acyloxyalkyl acylphosphonates as potential prodrugs of the antiviral, trisodium phosphonoformate (foscarnet sodium). Tetrahedron Lett., 30, 7141, 1989. [Pg.475]

These two compounds may possess some clinical advantage over ara-A due to their low systemic toxicity. The antiviral effects of phosphonoformic acid (PFA, foscarnet sodium), which is presently in Phase III clinical trials in Europe, 3 have been discussed in a recent review.91 The synthesis and structural requirements for antiherpes activity of a series of PFA esters have also been reported.92... [Pg.123]

See other pages where Foscarnet sodium phosphonoformate is mentioned: [Pg.1736]    [Pg.286]    [Pg.287]    [Pg.1736]    [Pg.286]    [Pg.287]    [Pg.183]    [Pg.184]    [Pg.2277]    [Pg.161]    [Pg.665]    [Pg.1121]   
See also in sourсe #XX -- [ Pg.76 , Pg.77 , Pg.184 ]



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