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Fosamax

Dronal (Sigmatau) Fosamax (Merck Sharp Dohme)... [Pg.54]

Alendronate (Fosamax, 5 mg daily, 35 mg weekly (prevention) to zero with food or beverage... [Pg.39]

Fosamax plus D) 10 mg daily, 70 mg tablet 70 mg tablet with vitamin intake-long T1/2 (<10 years) ... [Pg.39]

Alendronate (Fosamax) Anti-osteoporotic Bone stabilizer Tab 10.40 mg... [Pg.4]

Fosamax provides an example of how double-patenting with a terminal disclaimer may result in multiple 30-month stays. The brand-name company listed and initially sued on the earlier patent. No. 5,849,726 (the 726 patent), which claims a method for treating and/or preventing bone loss using the anhydrate form of alendronate sodium. The later patent. No. 6,008,207 (the 207 patent), was a continuation of the 726 patent. It claims a method for treating bone resorption and a method for... [Pg.128]

Alendronate (Fosamax, Fosamax Plus D) Raloxifene (Evista)... [Pg.46]

Uses Rx prevent osteoporosis male female, Rx steroid-induced osteoporosis, Paget Dz Action -1- N1 abnormal bone resorption Dose Osteoporosis Rx 10 mg/d PO or 70 mg qwk Fosamax plus D 1 tab qwk Steroid-induced osteoporosis Rx 5 mg/d PO Prevention 5 mg/d PO or 35 mg qwk Paget Dz 40 mg/d PO Caution [C, ] Not OK if CrCl <35 mLAnin, w/ NSAID use Contra Esophageal anomalies, inability to sit/stand upright for 30 min, X Ca Disp Tabs, soln SE GI disturbances, esophageal irritation, HA, pain, jaw osteonecrosis (w/ dental procedures, chemo) Interactions -1- Absorption W7 antacids, Ca supls, Fe, food T risk of upper GI bleed W/ ASA NSAIDs EMS May cause cardiac conduction abnormalities d/t T Ca T risk of jaw fractures esp w/ dental procedures OD May cause hypocalcemia and adverse upper-GI effects milk or antacids can be given to bind alendronate... [Pg.65]

Multiple bisphosphonates compounds are available for both oral and intravenous use. Some [alendronate (Fosamax) and etidronate (Didronel)] are used for osteoporosis, others [etidronate, tirludronate (Skelid), risedronate Actonel) for Paget s disease, and yet others [pamidronate Aredia), zoledronic acid] for the hypercalcemia of malignancy. [Pg.760]

Top 11-20 brands (all figures in billion) Ogastro/Prevacid (Takeda), 3.5 Effexor (Wyeth), 3.5 Procrit/Eprex (Johnson Johnson), 3.3 MabThera/Rituxan (Roche), 3.3 Zoloft (Pfizer), 3.3 Fosamax (Merck), 3.2 Singulair (Merck), 3 Cozaar+Hyzaar (Merck), 3 Seroquel (AstraZeneca), 2.8 Remicade (Johnson Johnson), 2.5 Lovenox (Sanofi-Aventis), 2.7. [Pg.98]

Fosamax 3.2 Topamax 1.7 Hyzaar 3.0 Aricept 1.9 Protonix 3.4 Lovenox 2.7... [Pg.187]

It makes Cozaar and Hyzaar for hypertension Vytorin, Zetia, and Zocor to lower cholesterol Pro-pecia for male-pattern baldness Singulair for asthma Fosamax for osteoporosis and Gardasil, a vaccine for cervical cancer but it is also well known for making Vioxx, a pain relief drug taken off the market for causing heart problems. [Pg.211]

General Category Bisphosphonates Examples Alendronate (Fosamax) Etidronate (Didronel) Ibandronate (Boniva) Pamidronate (Aredia) Risedronate (Actonel) Treatment Rationale and Principal Indications Appear to block excessive bone resorption and formation is used to normalize bone turnover in conditions such as osteoporosis and Paget disease, and to prevent hypercalcemia resulting from excessive bone resorption in certain forms of cancer... [Pg.468]

The bisphosphonates (also called diphosphonates) are a group of inorganic compounds that include alendronate (Fosamax), pamidronate (Aredia), and several... [Pg.469]


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Fosamax Plus D

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