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Alendronate sodium

NL has osteoporosis that is being managed with sodium alendronate (Fosamax), and fortunately, the... [Pg.879]

An efficient synthesis of sodium alendronate (276), an osteoporosis drug, has been developed through counterattack reaction involving treatment of the respective acyl phosphonate (275), obtained from the carbocylic acid (274), with P(OMe)3 and TMSBr followed by deprotection of the bisphosphonate ester with aqueous HCl (Scheme 96). ... [Pg.293]

CH4O3S 75-75-2) see Alatrofloxacin mesilate Alendronate sodium Dolasetron mesilate Glaziovine Nelfinavir mesylate Tirilazad mesilate Trovafloxacin mesilate... [Pg.2406]

H2NNa 7782-92-5) see Milnacipran hydrochloride sodium 5-(3-aminopropyl)-4,6-dihydroxy-l,3,2,4,6-di-oxatriphosphorinan-5-olate 2,4,6-trioxide (C4H NNa08P3) see Alendronate sodium sodium azide... [Pg.2441]

US patent 6,696,601, Hydrate forms of alendronate sodium, processes for manufacture thereof, and pharmaceutical compositions thereof [102], New hydrate forms of alendronate sodium, having a water content of about 1-12%, and processes for their manufacture, are disclosed. New crystalline forms of alendronate sodium, and processes for manufacturing these, are also disclosed. These new forms of alendronate sodium are suitable for incorporation into pharmaceutical compositions for combating bone resorption in bone diseases. [Pg.277]

Fosamax provides an example of how double-patenting with a terminal disclaimer may result in multiple 30-month stays. The brand-name company listed and initially sued on the earlier patent. No. 5,849,726 (the 726 patent), which claims a method for treating and/or preventing bone loss using the anhydrate form of alendronate sodium. The later patent. No. 6,008,207 (the 207 patent), was a continuation of the 726 patent. It claims a method for treating bone resorption and a method for... [Pg.128]

Bisphosphonates alendronate sodium clodronate disodium etidronate disodium pamidronate disodium risedronate sodium zoledronic acid... [Pg.606]

Alendronate sodium is indicated for prevention of glucocortoid-induced bone loss. Rapid bone loss occurs after transplantation, placing these patients at increased risk for fractures. Because of improving longterm survival, attention to metabolic bone disease should occur early in the posttransplant course so that the risk of complications might be lessened. [Pg.85]

See other pages where Alendronate sodium is mentioned: [Pg.336]    [Pg.10]    [Pg.16]    [Pg.1087]    [Pg.1118]    [Pg.70]    [Pg.336]    [Pg.10]    [Pg.16]    [Pg.1087]    [Pg.1118]    [Pg.70]    [Pg.53]    [Pg.53]    [Pg.2290]    [Pg.2297]    [Pg.510]    [Pg.581]    [Pg.620]    [Pg.583]    [Pg.262]    [Pg.191]    [Pg.99]    [Pg.123]    [Pg.355]    [Pg.29]    [Pg.471]    [Pg.973]    [Pg.83]    [Pg.86]    [Pg.1032]    [Pg.141]    [Pg.141]    [Pg.142]    [Pg.142]    [Pg.142]   
See also in sourсe #XX -- [ Pg.336 ]



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