For thallium poisoning

A variety of therapies for thallium poisoning have been suggested by neutralising thallium in the intestinal tract, hastening excretion after resorption, or decreasing absorption. Berlin-Blue (fertihexacyanate) and sodium iodide in a 1 wt % solution have been recommended. Forced diuresis hemoperfusion and hemodialysis in combination results in the elimination of up to 40% of the resorbed thaHous sulfate (39). 

Dithranol Ointment, B.P. dithranol. dithranol triacetate dithranol. ditiocarb sodium [inn] (sodium dlethyldithiocarbamate dithiocarb OTC) is a chelating agent used as an ANTIDOTE for thallium poisoning. It is also an (immunostimulant) IMMUNOMODULATOR. 

It is indicated in metallic intoxication due to arsenic, mercury, gold, bismuth, lead, nickel, thallium and antimony in conjunction with sodium calcium edetate for lead poisoning. It is also useful in hepatolenticular degeneration (Wilson s disease). It is contraindicated in iron and cadmium poisoning. 

Thompson DF, Called ED Soluble or insoluble Prussian blue for radiocesium and thallium poisoning Ann Pharmacother 2004 38 1509. [PMID 15252192]... 

The development of chelating agents for use in metal ion removal is still in its infancy and suitable antidotes are not yet available for treating poisoning by beryllium, cadmium, manganese, thallium and many other toxic metal ions. Radiostrontium and radium pose particular problems because of their chemical similarities to calcium. 

Thallium, atomic no. 81 This element is better known for its poisonous properties and links with almost undetected deaths and Agatha Christie -type murder mysteries.2 Thallium compounds are used in some countries as cheap insecticides, particularly for killing cockroaches. Intake of this element causes stomach pains, vomiting and nausea, painful soles and palms of hands, limb weakness, double vision, involuntary eye movements, hallucina tions, characteristic hair loss and white lines across the nails. The symptoms are often mis-diagnosed as other diseases. Treatment is with the chemical Prussian Blue... 

In biological systems, thallium is nonessential, (i.e., not required for organisms to complete their fife cycles) and toxic at high concentrations. Thal-fium(I) mimics potassium. In humans it affects potassium-activated enzymes in the brain, muscles, and skin. Symptoms of thallium poisoning can easily be attributed to other causes, which in the past has made this element popular for homicides ... 

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