Nomenclature folic acid

Nomenclatuie and symbols foi folic acid assigned based on lecommendation published by lUPAC-lUB joint commission on Biochemical Nomenclature 1986 (20,21). 

Nomenclature and symbols for folic acid and related compounds... 

Nomenclature of Carbohydrates http //www.chcm.qinul.ac.Lik/iupac/2carb/ Nomenclature of Carotenoids http //www.chcin.qmul.ac.uk/iiipac/carot/ Nomenclature and Symbols for Folic Acid and Related Compounds http //www. chem.qmul.ac.uk/iupac/misc/folic.html... 

The answer is e. (Murray, pp 627-661. Sciiver, pp 3897-3964. Sack, pp 121-138. Wilson, pp 287-320.) Ascorbic acid (vitamin C) is found in fresh fruits and vegetables. Deficiency of ascorbic acid produces scurvy, the sailor s disease. Ascorbic acid is necessary for the hydroxylation of proline to hydroxyproline in collagen, a process required in the formation and maintenance of connective tissue. The failure of mesenchymal cells to form collagen causes the skeletal, dental, and connective tissue deterioration seen in scurvy. Thiamine, niacin, cobalamin, and pantothenic acid can all be obtained from fish or meat products. The nomenclature of vitamins began by classifying fat-soluble vitamins as A (followed by subsequent letters of the alphabet such as D, E, and K) and water-soluble vitamins as B. Components of the B vitamin fraction were then given subscripts, e.g., thiamine (Bi), riboflavin (B2), niacin [nicotinic acid (B3)], panthothenic acid (B5), pyridoxine (Bg), and cobalamin (B ). The water-soluble vitamins C, biotin, and folic acid do not follow the B nomenclature. 

Nomenclature. Folic acid, pteroylglutamic acid (PteGlu) folates also used as a group name for a family of more than 100 related compounds that have been modified on the pterin moiety, on N-5 and/or N-10, and on glutamyl side-chain. 

The enzymatic roles of the folate coenzymes were first studied in connection with purine nucleotide biosynthesis, although some of the major manifestations of folate deficiency are due to impairment of thymidylate and DNA synthesis. Figure 5-1 shows the structure of folic acid and identifies its component parts. Nomenclature in this area has changed frequently and is sometimes confusing and inconsistent Table 5-1 gives the latest approved nomenclature, together with alternatives also found in the literature. The field of folic acid biochemistry is discussed in depth by Blakley (2). 

Nomenclature of Vitamins, Coenzymes and Related Compounds Trivial Names of Miscellaneous Ck)mpounds of Importance in Biochemistry, Nomenclature of (Quinones with Isoprenoid Side CSiains, Nomenclature and Symbols for Folic Acid and Related Compounds, Nomenclature of Corrinoicls [see Eur. J. Biochem. 2 (1967) 1]. 

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