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Fluxome Analysis

Lysine Glucose Systems biology profiling of a production process with transcriptome, metabolome, and fluxome analysis [76]... [Pg.35]

Fluxome Analysis Using Isotope Labelling Methods... [Pg.154]

Wittmaim, C. (2007) Fluxome analysis using GC-MS. Microb. Cell Fact.,... [Pg.216]

Metabolome represents the entire set of low-molecular-weight metabolites that are present in a cell and/or outside the cell under particular conditions [30]. Metabolite profiling allows comparative analysis of physiological states under different conditions e.g., a wild-type vs its mutants, and different culture conditions. Fluxome, the entire set of metabolic fluxes, can also be used for understanding the cellular... [Pg.5]

Kromer JO, Sorgenfrei O, Klopprogge K et al (2004) In-depth profiling of lysine-producing Corynebacterium glutamicum by combined analysis of the transcriptome, metabolome, and fluxome. J Bacteriol 186 1769-1784... [Pg.18]

Proteomics and metabolomics detect only a small subset of the total proteome and metabolome, and fluxomics (metabolic flux analysis) tends to focus on discrete pathways determined in part by the substrates that are used for the analysis. To date, gel-based proteomic analysis ranains... [Pg.486]

The mathematic behind this analysis used experimentally measured C-based flux distributions (v) and the set of ecologically competitive elementary modes ( ) identified through paired cost miiumizations. The fluxomic data described the E. coli central carbon metabolism using ten degrees of freedom the EFMs were projected into the same ten dimensional space to permit comparison. The proportional contributioi of each individual EFM to the overall phenotype is given by a weighting vector w such that ... [Pg.150]

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Fluxomics

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