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Fluvastatin Alcohol

Alcohol does not significantly interact with fluvastatin. [Pg.63]

Smit JWA, Wijnne HJA, Schobben F, Sitsen A, de Bruin TWA, Erkelens DW. Effects of alcohol consumption on pharmacokinetics, efficacy, and safety of fluvastatin. Am J Cardiol... [Pg.63]

Fluvastatin (28, Scheme 2.4) is a member of the 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG CoA) reductase inhibitor family and is prescribed to treat hypercholesterolemia. As part of their nonracemic synthesis of fluvastatin, researchers at Novartis used a monoacetyltri-phenylglycol chiral auxiliary 25 originally reported by Braun and Devant. A diastereoselective lithium aldol reaction between Braun and Devant s reagent 25 and the fluarophenylindolenal 24 afforded the allylic alcohol 26 as... [Pg.48]

See other pages where Fluvastatin Alcohol is mentioned: [Pg.176]    [Pg.236]    [Pg.63]    [Pg.63]    [Pg.56]   
See also in sourсe #XX -- [ Pg.63 ]



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