Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

4-Fluoro-4- butanone

C H4pN02 350-46-9) see Nitrefazole Pioglitazonc l-[5-fluoro-2-(oxiranylmethoxy)phenyl]-l-butanone (CjjHijFOt 94135-58-7) see Butofilolol... [Pg.2387]

Comparable effects were observed in the catalysis of the dehydrofluorination of 4-fluoro-4-(p-nitrophenyl)-2-butanone using Mi-polymers or even Ml-pro-teins (see later) imprinted with suitable TSA templates. Focusing on the two sp3 hybridized carbons (C2 and C3) of the butanone which are converted to sp2 carbons as a result of dehydrofluorination, the search for the right TSA led to N-benzyl-AT-isopropylamine (Fig. 13) either containing a nitro-group [62] at the aromatic ring or not [63,64]. [Pg.150]

Fig. 14. Application of an AT-benzylisopropylamine imprinted MAA/EGDMA copolymer as catalyst for the dehydrofluorination of 4-fluoro-4-(p-nitrophenyl)-2-butanone in a batch reactor. Given is the substrate concentration versus time. The reaction was carried out at 50° C in 10 ml of a mixture of water and acetonitrile 1 1 (v/v), containing 5 mg of the substrate 4-fluoro-4-(p-nitrophenyl)-2-butanone (i. e., a final concentration of 2.4 mmol/1) and 500 mg MIP or non-im-printed control polymer (CP). Top use of MIP, 1. experiment ( ), 2. experiment ( ). Bottom use of CP, 1. experiment ( ), 2. experiment ( ). Reprinted with permission from Briiggemann O (2001) Anal Chim Acta 435 197. Copyright 2001 Elsevier Science... Fig. 14. Application of an AT-benzylisopropylamine imprinted MAA/EGDMA copolymer as catalyst for the dehydrofluorination of 4-fluoro-4-(p-nitrophenyl)-2-butanone in a batch reactor. Given is the substrate concentration versus time. The reaction was carried out at 50° C in 10 ml of a mixture of water and acetonitrile 1 1 (v/v), containing 5 mg of the substrate 4-fluoro-4-(p-nitrophenyl)-2-butanone (i. e., a final concentration of 2.4 mmol/1) and 500 mg MIP or non-im-printed control polymer (CP). Top use of MIP, 1. experiment ( ), 2. experiment ( ). Bottom use of CP, 1. experiment ( ), 2. experiment ( ). Reprinted with permission from Briiggemann O (2001) Anal Chim Acta 435 197. Copyright 2001 Elsevier Science...
Fluoro-3-methylsulphinyl-4-quinolone (5.0 g) was dissolved in hot butanone (250 ml) containing anhydrous potassium carbonate (3.06 g). The resulting suspension was stirred and treated dropwise with dimethyl sulphate (2.09 ml). The mixture was stirred and boiled under reflux for 1 hour and filtered while hot. The filtrate was allowed to cool, giving a crystalline product. The product was collected and dried to give 7-fluoro-l-methyl-3-methylsulphinyl-4-... [Pg.1625]

SYNS AZAPERONE (USDA) DAZEPERONE EUCALMYL FLUOPERIDOL l-(3-(4-FLUORO-BENZOYL)PROPYL)-4-(2-PYRIDYL)PIPERAZINE l-(4-FLUOROPHENYL)-4-(4-(2-PYRIDINYL)-l-PIPERAZINYL)-1-BUTANONE R 1929 STRESNIL SUICAIAI... [Pg.673]

The catalysis of some other reactions by imprinted polymers also showed promising results. The dehydrofluorination of 4-fluoro-4-(4-nitrophenyl)butanone... [Pg.102]

C6H120 3,3-dimethyl-2-butanone 75-97-8 221.15 11.330 1 8715 C6H13F 3-fluoro-3-methyl pentane 19031-61-9 191.45 6.962 2... [Pg.563]

The reaction between a-halo ketones and sodium dialkyl phosphites has been extended to phosphonate carbanions. For example, diisopropyl 1 -lithio-1-fluoromethylphosphonate, generated from diisopropyl fluoromethylphosphonate and LDA, reacts with 3-chloro-2-butanone at low temperature in THF to give diisopropyl l-fluoro-2-nicthyl-2,3-cpoxybutylphosphonate in 46% yield. 33.134... [Pg.165]

Pipamperone, I. [4.(4-Fluorophenyl)-4-oxobut-< - 1,4 -bipiperidineJ-4 -carboxamide 1 -[3-(p-fluoro-benzoyl)propyl]-[I,4 -bipiperidine]-4 -carboxamide l -ip-fluorophenyl)-4-(4 -piperidino-4 -carbamoylpiperidino)-l butanone l [7-(4-fluorobenzoyl)propyl] -4-piperidinopiper-idine-4-carboxamide 4 -fluoro-4-(/V-[4-(lV-piperidino)-4-carbamido]piperidino]butyrophenone floropipamide R 3345 Dipiperon Piperonyl Prop tan C1,H30FNjOj mol wt 375,49. C 67.17%, H 8.05%, F 5.06%, N 11.19%, 6 8.52%. Prepn of the dihydrochloride by reaction of y-chloro-4-fluorobutyrophenone and 4-piperidinopiperidine-4-carbox-... [Pg.1183]

Timiperone, 4-[4-(2,3-Dihydro-2-ihioxo-IH-benzimidazol-l yl -I-piperidlnyl]-I-(4-fluOropheHyt )-l-butanone 1 -[ 1 -[3-(4-fluoro benzoyl )propy l] -4 - pi peri dy l] -2 -me reap to benzimidazole 4-fluoro -4 -(2-thioxo -benz-... [Pg.1488]

Better results were obtained for the catalysis of the dehydrofluorination of 4-fluoro-4-(4-nitrophenyl)butanone by Shea et al. [94] and Mosbach et al [147]. Shea used benzyl-malonic acid as the template to position two polymerizable amines in a definite arrangement in the cavity. After removal of the template, dehydrofluorination was enhanced by this catalyst by a factor of 8.6. [Pg.61]

The stable nitroxide (CF3)2NO reacts with a variety of fluorinated acetylenes, as well as with fluoro-olefins. Pcrfluorobut-2-yne is converted by this reagent mainly into perfluorobiacetyl (73%) and the butanone (168) (20%), probably by the route shown in Scheme 51. In a slower reaction with... [Pg.117]

N-Benzyl- isopropylamine 4-Fluoro-4- (p-nitro-phenyD- 2-butanone kimp/ knonimp < 2.4 63... [Pg.155]

Cyano[ fluoro-3,3 -(trhnethylenedinitrilo)bis(2-butanone oximato)borato]copper(n) Cu, 2.042(8), square pyramidal... [Pg.365]

Antipsychotic drug enzymatic reduction of 1-(4-fluorophenyl) 4-[4-(5-fluoro-2-pyrimidinyl) 1 -piperazinyl]- -butanone. [Pg.95]

Butanone, 4-14-14-chlorophenyl) -4-hvdroxy-1-piperidinvH-1-l4-fluoro phenyl)- (9CI)... [Pg.156]

See other pages where 4-Fluoro-4- butanone is mentioned: [Pg.205]    [Pg.152]    [Pg.1697]    [Pg.193]    [Pg.563]    [Pg.204]    [Pg.204]    [Pg.204]    [Pg.204]    [Pg.6]    [Pg.914]    [Pg.985]    [Pg.240]    [Pg.95]    [Pg.108]   
See also in sourсe #XX -- [ Pg.58 , Pg.60 , Pg.60 ]



SEARCH



4-Fluoro-4- butanone dehydrofluorination

Butanon

Butanone

Fluoro-2-Pyrimidinyl)1-Piperazinyl-1-Butanone

© 2024 chempedia.info