Fluoride ions biological fluids related

Other alterations in biological fluids related to fluoride ions... [Pg.280]

Several experiments have shown the bactericidal effect of fluoride ions at high concentrations [180,181]. This effect generally occurs at concentrations well above those generally observed in saliva however, the use of fluoridated toothpaste or dental topical applications of fluoride may temporarily elevate the fluoride concentration in the oral cavity to bactericidal levels. It has been demonstrated that fluoride affects the metabolism of oral bacteria and reduces its acid tolerance. It is most effective at acidic pH values and, for example, fluoride levels as low as 0.1 mM can cause the complete arrest of glycolysis by Steptococcus mutans. It has been suggested that modifying the biological fluids related to the presence... [Pg.320]

The only wide-range application and commercialisation area of fluoride-containing biomaterials concern ionomer glasses for dental applications. The improved biological effect of these compounds is related to a slow release of active fluoride ions in biological fluids and the direct effect of fluoride ions on mineralised biological tissues. [Pg.322]

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