Fluorescence Chemosensing of Carbohydrates

Few chemical sensing mechanisms (other than bulk quenching) have been described for neutral molecules nevertheless, many small analytes of interest are uncharged glucose, for example. Of course, most carbohydrates are neither fluorescent nor are they fluorescence quenchers novel signal transduction mechanisms are required. 

The experimental and intellectual contributions of Drs. Xavier Cherian, Engin Akkaya, Mike Huston, Mi-Young Chae, Juyoung Yoon, Sung Yeap Hong, and Scott Van Arman are represented by the work described in this chapter. We gratefully acknowledge support for this work from The Ohio State University, the A. P. Sloan Foundation, the Camille and Henry Dreyfus Foundation, the National Science Foundation, Merck Co., and Eli Lilly and Company. 

Schwarzenbach and H. Flaschka, Complexometric Titrations (H. Irving, trans.), Methuen, New York (1969) (b) T. S. West, Complexometry with EDTA and Related Reagents, BDH, New York (1969) (c) Indicators (E. Bishop, ed.), Chapter 6, Pergamon, Oxford (1972) (d) G. G. Guilbault, Practical Fluorescence, Chapter 6, Marcel Dekker, Inc., New York (1973) (e) R. J. Clarke, J. H. Coates, and S. F. Lincoln, Inorg. Chim. Acta, 153, 21 (1988). 

Gordon and W. R. Ware, eds. The Exciplex, Academic Press New York (1975). 

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