Flow cells, detectors refractive index effects

Gow-Mac has recently marketed a refractometer which is based on the Christiansen effect . The system consists of a sample flow cell which is packed with a solid material having the same refractive index as the mobile phase. Visible light is therefore transmitted directly through the cell. When a solute enters the cell, the refractive index of the mobile phase alters, causing a change in the quantity of transmitted light which reaches the detector. A variety of solid materials is available for use with a large number of solvent systems. 

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