Flaxseed diglucoside

Degenhardt, A., Habben, S., and Winterhalter, P. 2002. Isolation of the lignan secoisolariciresinol diglucoside from flaxseed (Linum ustitatissimum L.) by high-speed counter-current chromatography. J. Chromatogr. 943, 299-302. [Pg.80]

Eliasson, C., Kamal-Eldin, A., Andersson, R., and Aman, P. 2003. High-performance liquid chromatographic analysis of secoisolariciresinol diglucoside and hydroxycinnamic acid glucosides in flaxseed by alkaline extraction. J. Chromatogr. 1012, 151-159. [Pg.81]

Madhusudhan, B., Wiesenbom, D., Schwarz, J., Tostenson, K., and Gillespie, J. 2000. A dry mechanical method for concentrating the lignan secoisolariciresinol diglucoside in flaxseed. Leb. Wiss. Tech. 33, 268-275. [Pg.87]

Prasad, K. 1999. Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed. Circulation 99, 1355-1362. [Pg.90]

Prasad, K. 2001. Secoisolariciresinol diglucoside from flaxseed delays the development of type 2 diabetes in Zucker rat. J. Lab. Clin. Med 138, 32-39. [Pg.91]

Prasad, K., Mantha, S.V., Muir, A.D., and Westcott, N.D. 1998. Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alpha-linolenic acid. Atherosclerosis 136, 367-375. Prasad, K., Mantha, S.V., Muir, A.D., and Westcott, N.D. 2000. Protective effect of secoisolariciresinol diglucoside against streptozotocin-induced diabetes and its mechanism. Mol. Cell. Bio-chem. 206, 141-150. [Pg.91]

Johnsson, P. Kamal-Eldin, A. Lundgren, L.N. Aman, P. 2000. HPLC method for analysis of secoisolariciresinol diglucoside in flaxseeds. J. Agric. Food Chem. 48 5216-5219. [Pg.98]

Teoh, K.H., Ford, J.D., Kim, M.R., Davin, L.B. and Lewis, N.G. (2003) Delineating the metabolic pathway(s) to secoisolariciresinol diglucoside hydroxymethyl glu-tarate oligomers in flaxseed (Linum usitatissimum), in Flaxseed in Human Nutrition (eds L.U. Thompson and S.C. Cunnane), 2nd edn. AOGS Fress, Ghampaign, pp. 41-62. [Pg.253]

Lignans of flaxseed exist as secoisolariciresinol diglucoside (SDG 126). SDG is a potent antioxidant in biological systems because of its tendency to associate in the aqueous phase. Much of the work on antioxidant activity of SDG is related to its radical mediated disease prevention (127, 128). Lignans of both sesame (121, 122) and flax (129, 130) have shown hydrogen-donating abihty and scavenging activity for various free radicals. [Pg.507]

Fritsche, J. Angoelal, R. Dachtler, M. On-hne hquid chromatography-nuclear magnetic resonance spectroscopy-mass spectrometry coupling for the separation and characterization of secoisolariciresinol diglucoside isomers in flaxseed. J. Chromatogr. A, 2002, 972, 195-203. [Pg.1351]

Secoisolariciresinol diglucoside was isolated from flaxseed and analyzed on a 25°C C]g column (A = 280nm) using a 30-min 100/0- 70/30 water (lOmM phosphate at pH 2.8)/acetonitrile gradient [1219]. Peak shape was good as was the overall resolution. Standards of 20-160pg/mL were used. [Pg.435]

Bakke, J.E. and Klosterman, H.J. A new diglucoside from flaxseed. Proc. North Dakota Acad. Sci. 1956, 10, 18-22. [Pg.323]

Both END and ENL enantiomers are produced by bacteria, and the human exposure to the enantiomers results from the interaction of the initial type of substrate and the composition of the bacterial consortia. For example, (—) ENL predominates in serum when humans consume their habitual diets, but when supplemented with flaxseed the (-I-) ENL form increases substantially with comparatively modest increases in ( —) ENL. Additionally, the forms of END and ENL that have been isolated as the result of incubating SEXU with intestinal bacteria produce (+) END and (-I-) ENL. However, if the lignans arctiin or PINO diglucoside are used as a substrate (—) END and (—) ENL are produced. Subsequently, some bacteria have shown enantiomeric selectivity when converting lignans. Ruminococcus sp. END-1 enantioselectively converts (-) END to (-) ENL, while the strain END-2 converts (+) END to (-I-) ENL. EggertheUa sp. SEKi-2 can convert (-I-) dihydroxyenterodiol (DHEND)... [Pg.105]

Nemes SM (2007) Microwave-assisted extraction (MAE) of secoisolariciresinol diglucoside (SDG) from flaxseed. McGill University, Montreal/Quebec... [Pg.2042]

FIGURE 1.4 Biosynthesis of the lignan secoisolariciresinol diglucoside (SDG) in flaxseed. (From Ford, T.D., Davin, L.B., and Lewis, N.G., Proc. 58th Flax Inst. United States, March 23-25, Fargo, ND, 39 8, 2000.)... [Pg.12]

Bambagiotti-Alberti, M., Coron, S.A., Ghiara, C., GianneUini, V., and RaffaeUi, A., Revealing the mammaUan lignan precursor secoisolariciresinol diglucoside in flaxseed by ionspray mass spectrometry. Rapid Commn. Mass Specrom., 8, 595-598, 1994a. [Pg.71]

Coran., S.A., Gianenellini, V., and Bambagiotti-Albert, M., High-performance thin-layer chromatographic-densitometric determination of secoisolaricitesinol diglucoside in flaxseed, J. Chromatogr. A, 1045, 217-222, 2004. [Pg.72]

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