Fischer, Emil Hermann

Fischer, Hermann Emil (1852-1919) German organic chemist who discovered the molecular structures of sugars, including glucose, found the structure of purines, isolated and identified amino acids, and worked on the structure of proteins. He received the Nobel Prize in chemistry in 1902 for his work on sugars and purines. 

Hermann Emil Fischer Germany sngar and purine syntheses... 

Fischer projections (after the German chemist Hermann Emil Fischer) is an ingenious means for... 

Hermann Emil Fischer (1852-1919), Germany. In recognition of the extraordinary services he has rendered by his work on sugar and purine syntheses. ... 

Hermann Emil Fischer (Germany) for his work on sugar and purine syntheses. Fischer showed that various molecules from plants and animals, which were initially not believed to be related, were in fact structurally similar. He went on to show that various sugars could be made in the lab from simple chemicals like urea. With the ability to make sugar molecules, he proceeded to establish the three dimensional structure of every known sugar. 

Hermann Emil Fischer (1852-1919), German chemist and founding father of the domain of molecular recognition. Known mainly for his excellent work on the structure of sugar compounds. His correct determination of the absolute conformation of sugars (recognized decades later) was based solely on the analysis of their chemical properties. Even today, this would require advanced physicochemical investigations. In 1902, Fischer received the Nobel... 

Finally, a few words should be offered on the mysterious substance of thein. Actually, this is the same as caffeine, and articles attributing special effects to thein have no scientific credibility. Thein was identified by a researcher named M. Oudiy in 1827 as the ingredient responsible for the stimulating effect of tea. However, later it was shown to be identical to caffeine, which was also discovered in the 1820s. German Nobel laureate Hermann Emil Fischer (1852-1919) explored the chemical structure of caffeine at the end of the nineteenth century, and also synthesized it... 

The evidence that in natural products, especially in primary metabolites, some structural patterns are repeated in different structures, implies that most organisms have common biosynthetic pathways. At the end of the nineteenth century when the biosynthetic pathways were not known, Heinrich Kiliani and Hermann Emil Fischer developed a simple model which could explain how stereochemically pure long-chained monosaccharides can form from simple molecules. The simplest, parent monosaccharide is aldotriose with only one chiral carbon atom. Hence, there are D- and L-aldotrioses. Since aldotriose is the product of mild oxidation of glycerol it can also be called glyceraldehyde. 

Hermann) Emil Fischer was bom on October 9, 1952, at Euskirchen, in the Cologne district of Germany. The family was Protestant and had been in the Rhineland since the end of the seventeenth century. Fischer was the son of Laurenz Fischer, a successful merchant, and Julie Poensgen Fischer. Hie family consisted of the parents, one son, Emil, and five dau ters. The son had a pleasant youth his pla3miates were mostly his numerous cousins. The friendship with one cousin, Otto Philipp Fischer, developed into a cooperative relationship in university studies and research. 

Hermann Emil Fischer (1852-1919), German chemist and founding father of the domain of molecular recognition. Known mainly for his excellent work on the structure of sugar compounds. 

The excellence of German chemistry in general, not just of its organic branch, is objectively attested by its share of Nobel Prizes during the first two decades of the award s existence. Of the seventeen prizes awarded between 1901 and 1921 nine were to German chemists Hermann Emil Fischer (1902), Johann Friedrich Wilhelm von Baeyer (1905), Edward Buchner (1907), Wilhelm Ostwald (1909), Otto Wallach (1910), Alfred Werner (1913), Richard Will-statter (1915), Fritz Haber (1918), and Walther Nemst (1920). 

The natural substrate for the dehydrogenase, glyceraldehyde-3-phosphate (G-3-P), had been synthesized earlier by Hermann Fischer, Emil Fischer s son, and Baer in 1932. In 1934 Meyerhof and Lohmann synthesized hexose diphosphate, establishing it to be fructose 1,6 bisphosphate (F-l, 6 bis P). With F-1,6 bisP as substrate and hydrazine to trap the aldehydic and ketonic products of the reaction, G-3-P was identified in the mixture of G-3-P and dihydroxyacetone phosphate which resulted. Triose phosphate isomerase was then isolated and the importance of phosphorylated 3C derivatives established. 

Ten years ago Kawamura (1 ) published a brief historical review on this reaction in memory of the sixtieth anniversay of its first report by Louis-Camille Maillard (2. The first Maillard paper was presented on January 8, 1912, by Armand Emile Justin Gautier (1837-1920) in a session of the Academy of Sciences in Paris. Six weeks earlier (November 27, 1911) a remarkable study was reported by Maillard (3) on the condensation of amino acids by use of glycerol. The method of peptide synthesis by Emil Hermann Fischer (1835-1919) was known to him. However, Maillard searched for milder conditions. 

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