Ferrous sulfate oral solution

Bubble nitrogen throughout the process. Check and record pH of item 10 (limit 5.0 to 6.5). 

Dissolve item 5 in 273.33 g of item 10 (30° to 35°C). Then add item 1 to the clear solution and dissolve slowly without aeration. 

Transfer the filtered drops in storage vessel under nitrogen blanket. 

Use nitrogen blanket in the tank throughout the storage and filling period. 

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Using a radioiron technique (15), 105 mg of iron as ferrous sulfate embedded in resin to form a tablet was better absorbed when 500 mg of ascorbic acid was incorporated into the preparation as compared with resin-embedded ferrous sulfate or an aqueous solution of ferrous sulfate. In the treatment of iron deficiency anemia, a more rapid repletion of hemoglobin was found when 500-750 mg of supplementary vitamin C was given prior to an oral dose of therapeutic metallic iron (16). 

Oral iron preparations Ferrous sulfate (tablets) Ferrous fumarate (tablets) Ferrous gluconate (tablets) Ferrous glycine sulfate (tablets or solution) Ferrous succinate (solution ) Sodium ironedetate (solution) Iron(ii) sulfate (40-105 mg Fe ) Iron(ii) fumarate (65-10 mg Fe ) Iron(ii) gluconate (35 mg Fe) Iron(n) glycine sulfate (25 100 mg Fe ) Iron(ii) succinate (37 mg Fe) Iron(n) chelate of ethylenediaminetetraacetic acid (FLDTA) (27.5 mg Fe)... 

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