Fatigue Smith

Mr. Smith is 28 years old and has no active medical problems. He has been treated with Li+ for manic-depressive illness for 1 year, and his mood has been stable. He now reports the gradual onset of fatigue, weight gain, and cold intolerance. Which single laboratory test is most likely to lead to the correct diagnosis ... 

Amphetamine, a Schedule II drug, was synthesized by the German chemist . Edeleano in 1887 (Figure 6.2). The trade names for amphetamine are Benzedrine and Dexedrine. Smith, Kline, and French marketed Benzedrine inhaler in the 1930s for respiratory disorders. Since amphetamine decreases drowsiness and fatigue, it is marketed for narcolepsy and attention-deficit/hyperactivity disorder (ADHD), and was used as an appetite suppressant (anorectic) in diet regimens. Amphetamine was supplied to the... 

R.A. Smith et al Experimental and theoretical fatigue-crack propagation lives of variously notched plates. J. Strain Ana. Eng. Dsgn. 9, 61-66 (1974)... 

Weston, A.R., O. Karamizrak, A. Smith, T.D. Noakes, and K.H. Myburgh (1999). African runners exhibit greater fatigue resistance, lower lac-... 

Neurotoxicity. The only available information regarding neurotoxicity of workers exposed to tetryl dusts, primarily via inhalation, were occasional irritability, headaches, nausea, vomiting, fatigue, and insomnia (Bergman 1952 Brabham 1943 Cripps 1917 Hardy and Maloof 1950 Hilton and Swanston 1941 Murray et al. 1944 Smith 1916 Witkowski et al. 1942). No other data in humans or animals were available. Because the effects noted in workers were minor and relatively nonspecific, it is not likely that the nervous system was a target of toxicity. Further studies in animals would be useful in understanding the neurotoxicity of tetryl. 

McEvily AJ jr. Boettner RC, Johnston XL (1964), In Burke JJ, Reed NL, Weiss V (eds) Fatigue — An Interdisciplinary Approach. Syracuse University Press, Syracuse, NY, p 95 Laird C, Smith GC (1962) Phil. Mag. 7 847 Jacoby G, Cramer Ch (1968) Rheologica Acta 7 23 Jacoby GH (1969) In ASTM STP 453. ASTM, Philadelphia, p 147... 

Gillson G, Richard TL, Smith RB, Wright JV (2002) A double-blind pilot study of the effect of Prokarin on fatigue in multiple sclerosis. Mult Scler Feb 8(l) 20-25. 

HaU PE, Kendall MJ, Smith SR. Beta blockers and fatigue. J Clin Hosp Pharm 1984 9(4) 283-91. 

Figure 7.30. Possible crack growth mechanism. [Adapted, by permission, from Xu X X, Crocrombe A D, Smith P A, Int. J. Fatigue, 16, No.7, 1994, 469-77.]...

Locci etal., 1993 Hack etal., 1993). The mechanical behavior of NiAl under complex conditions has not yet been studied systematically, as is exemplified by the only work on fatigue to date (Noebe and Lerch, 1992, 1993 Smith etal., 1992 Stoloff, 1992 Cullers et al., 1993 Edwards and Gibala, 1993). 

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