F Triethylamine

Hexafluoroacetone hydrate 25°C Hexafluoroacetone-water mixtures Hexafluoroacetone-sesquihydrate + triethylamine, 25°C Hexafluoroacetone-water (1 1.7 mol) -f triethylamine, 25°C p-Chlorophenol/2% a-pinene (60°C)... 

Elimination of hydrogen chloride from 2/f perfluoro-2-methylpropane-1 -sulfenyl chloride by the triethylamine-boron trifluoride complex results in cyclization to perfluoro-l,l-dimethylthiirane (perfluoroisobutylene sulfide) [, 9] (equation 9)... 

Fig. 2-7. Chromatograms of albuterol in the new polar organie phase on vaneomyein (A), teieoplanin (B), ristoeetin A (C), vaneomyein + teieoplanin (D), ristoeetin A + vaneomyein (E), and ristoeetin A + vaneomyein + teieoplanin (F). All eolumns were 100 x 4.6 mm. The numbers by the peaks refer to the retention time in minutes. The mobile phase was methanol with 0.02 % glaeial aeetie aeid and 0.01 % triethylamine (v/v). The flow rate was 2.0 mL min at ambient temperature (23 °C).

The action of triethylamine or 4-methylmorpholine on the imidazole derivatives 1 results in the formation of 4,5-dihydro-l/f-l,2-benzodiazepines 2, which eliminate imidazole on heating with ethanolic sodium ethoxide to give H-, 2-benzodiazepines 3.121 Details for compound 3 (R1 = Ph, R2 = Me) only were reported it was stated that other derivatives were obtained similarly but details were not given. 

Kinetic studies also provide other evidence for the SnI mechanism. One technique used F NMR to follow the solvolysis of trifluoroacetyl esters. If this mechanism operates essentially as shown on page 393, the rate should be the same for a given substrate under a given set of conditions, regardless of the identity of the nucleophile or its concentration. In one experiment that demonstrates this, benzhy-dryl chloride (Ph2CHCl) was treated in SO2 with the nucleophiles fluoride ion, pyridine, and triethylamine at several concentrations of each nucleophile. In each case, the initial rate of the reaction was approximately the same when corrections were made for the salt effect. The same type of behavior has been shown in a number of other cases, even when the reagents are as different in their nucleophilicities (see p. 438) as H2O and OH . 

Phenyl-l,2,4-triazine 4-oxide 91 reacts with l,3-dimethyluracil-6-hydrazones 92 in DMF in the presence of triethylamine to give pyrazolo[3,4-. 

In fact, fluorinated polyphosphazenes are usually considered to be extremely stable towards chemical agents and aggressives due to the presence of C-F bonds in the side phosphorus substituents. PTFEP, for instance, appears to be completely insensitive to several, most common, solvents (aliphatic and aromatic hydrocarbons, alcohols and water), to acids (e.g. acetic acid), and to bases (e.g. pyridine and concentrated NaOH solutions), although some decomposition could be observed in triethylamine and in concentrated H2SO4 [41]. Phos-phazene fluoroelastomers, moreover, are known to be completely insoluble in aromatic solvents [533] and petroleum-resistant materials [502-506,552]. 

The N-oxide of l-pyrrolo[2,3-b]pyridine 936 is converted by the combination tri-methylsilylisothiocyanate Me3SiNCS 937/MeOCOCl to 21% 6-isothiocyanato-l-methoxycarbonyl-pyrrolo[2,3-b]pyridine 938 and 18% 6-chloro-l-methoxycarbonyl-pyrrolo[2,3-F]pyridine 939 [51] (Scheme 7.14). To avoid formation of the chloro compound 939 a reagent combination of MesSiNCS 937 with triethylamine or DBU, which lacks any competing chloride ion, might give much higher yields of... 

The indenobenzazepines 314, obtainable from the corresponding protoberberines (Sections V,F,2 and V,G,2), were converted to the spirobenzyliso-quinolinediones 315 in 76% yield through hydrolytic bond cleavage and recyclization by sequential treatment with 4 N hydrochloric acid, bromine in acetic acid, and triethylamine, via the indanediones (Scheme 58) (166). A one-step stereoselective rearrangement of an indenobenzazepine to a spirobenzylisoquinoline was developed by Blasko et ah (167). O-Methylfumarofine (316)... 

Kuo P-F, Chen C-C (2006) Generation of gold thread from Au(III) and triethylamine. Langmuir 22 7902-7906... 

Hydroxymethyl)furan, Triethylamine Jenzen, A. F. et al., J. Fluorine Chem., 1988, 38, 205-208 Reaction of sulfur tetrafluoride with 2-hydroxymethylfuran in presence of triethylamine at —50°C is explosive in absence of a solvent. 

The elaboration of 113 to (—)-kinamycins C, F, and J, is shown in Scheme 3.19. To access ( )-kinamycin C (3), the silyl ether function of 113 was cleaved with aqueous hydrochloric acid (95 %). Alternatively, treatment of 113 with lithium hydroxide served to liberate the phenol function and saponify the three acetate esters, to provide ( )-kinamycin F (6) in 92 % yield. Finally, acylation of the tertiary hydroxyl of 113 (acetic anhydride, triethylamine) afforded a tetraacetate. Cleavage of the silyl ether then provided ( )-kinamycin J (10) in 80 % over two steps. 

The inlet tube is then replaced by a 300-ml. dropping funnel containing 202 g. (2 mols) of triethylamine. The triethylamine is added dropwise to the reaction mixture. During the addition, the reaction mixture is stirred and cooled by ice or cold water. After addition of the triethylamine, 73 g. (1 mol) of f-butyl-amine is added through the dropping funnel over a period of one hour. The slurry is stirred for 2 hours at room temperature and then finally heated to reflux for a period of 40 hours. 

Ostensibly minor variations of a synthetic procedure sometimes can have significant consequences. For example, substituting KOCMe(CF3)2 for LiOC-Me(CF3)2 is believed [85] to lead to formation of the alkylidyne complex shown in Eq. 16 instead of the known [83] Mo(CH-f-Bu)(NAd)[OCMe(CF3)2]2 (Ad=ad-amantyl). A proton is likely to be transferred before formation of the final product, since it has been known for some time that both W(CH-f-Bu)(NAr)[OC-Me(CF3)2]2 and W(C-f-Bu)(NHAr)[OCMe(CF3)2]2 are stable species that cannot be interconverted in the presence of triethylamine [41]. In such circumstances the nucleophilicity of the alkoxide ion and the nucleophilicity and acidity of the alcohol formed upon deprotonation of the alkylidene will be crucial determinants of whether the imido nitrogen atom is protonated at some stage during the reaction. At this stage few details are known about side reactions in which amido alkylidyne complexes are formed. 

Our laboratories10 have developed a system separating erythromycin estolate, erythromycin base, and anhydroerythromycin on a silica gel 60 F-254 plate utilizing ethanol, methanol, triethylamine, 170 30 1. Visualization is made by spraying with 0.15% xanthydrol and 7.5% acetic acid in water. Table V summarizes the Rf s. 

---