Expectorant eucalyptus

Expectorants are the drugs which increase the production of bronchial secretion and reduce its viscosity to facilitate its removal by coughing. Expectorants can stimulate the expulsion of respiratory secretion either directly or reflexly. Certain volatile oils of plant origin such as oil of lemon, anise, eucalyptus by steam inhalation route increase the respiratory secretion by its direct action. Another compound, guaiacol, which is obtained from wood creosote or synthetically prepared, directly increase bronchial secretion and syrup tolu (Tolu balsum) act in same way. 

Limonene [138-86-3] - [ANALYTICALMETHODS - TRENDS] (Vol 2) -aroma chemical [PERFUMES] (Vol 18) -in Bergamot oil [OILS, ESSENTIAL] (Vol 17) -in caraway oil [OILS, ESSENTIAL] (Vol 17) -in asms oil [OILS, ESSENTIAL] (Vol 17) -in citronella oils [OILS, ESSENTIAL] (Vol 17) -in eucalyptus oil [OILS, ESSENTIAL] (Vol 17) -in expectorants [EXPECTORANTS, ANTITUSSIVES AND RELATED AGENTS] (Vol 9) -m jumperberry oil [OILS, ESSENTIAL] (Vol 17) -in lavender [OILS, ESSENTIAL] (Vol 17) -in lavender [OILS, ESSENTIAL] (Vol 17) -in lime oil [OILS, ESSENTIAL] (Vol 17) -in neroli oil [OILS, ESSENTIAL] (Vol 17) -m oilbanum [OILS, ESSENTIAL] (Vol 17) -in orange oil [OILS, ESSENTIAL] (Vol 17) -in sweet basil oil [OILS, ESSENTIAL] (Vol 17)... 

Eucalyptus leaves and oil are commonly used as an antiseptic, febrifuge, and expectorant. 

The oxide 1,8-cineole (also called eucalyptol) is often described as a skin irritant. It is a major component in Eucalyptus globulus (up to around 90%), which has GRAS (Generally Recognized As Safe) status. Within the oil it is attributed beneficial effects such as antiseptic and expectorant. The other components present are again the hydrocarbon terpenes a-pinene, limonene, cymene, phellandrene, terpinene and aromadendrene. 

Expectorant and antibacterial activities have been reported for eucalyptus oil and for eucalyptol, and eucalyptus oil is taken orally for catarrh or used as an inhalation. (See R05C.)... 

C,oH,gO, Mr 154.25, colorless oils with camphor-like odor, bicyclic monoterpene epoxides. 1,4-C., bp. 173-174 °C 1,8-C.,bp. 176-177 °C. 1,4-C. occurs in the essential oil of Fructus Cubebae [a drug obtained from fully grown but unripe fruits of the Indonesian endemic plant Piper cubeba (Piperaceae)] and 1,8-C. occurs to 40-60% in eucalyptus oils (Eucalyptus globulus, Myrtaceae). C. are used as expectorant for bronchial catarrh and as aroma substances in the perfume industry. 

Use For perfuming household articles, for technical perfuming for aromatizing confectionery ( eucalyptus sweets ) and oral hygiene products in medicine for rhinologic, balneotherapy, mouth and throat, broncho-logical, expectorant, and antirheumatic ointment uses as starting material for pure 1,8-cineole. 

Oxides The oxides in essential oils, e.g., 1,8-cineol (eucalyptol) in eucalyptus oil, are largely responsible for the expectorant characteristics of such oils. The structure of eucalyptol is given in Figure 7. 

Eucalyptus oil and eucalyptol reportedly have antiseptic (antibacterial) and expectorant... 

Both eucalyptus oil and eucalyptol are extensively used as expectorants and/or flavoring agents in cold and cough medicines (e.g., cough drops and syrups), vaporizer fluids, antiseptic liniments, ointments, toothpastes, and mouthwashes. Also widely used as fragrance components in soaps, detergents, creams, lotions, and perfumes, with maximum use levels of 1.0 and 1.6% in perfumes reported for eucalyptus oil and eucalyptol, re-spectively. ° Eucalyptus oil and eucalyptol are used in dentistry as components of certain root canal sealers also used as solvents for root canal flllings. 

The anhydride of terpin, cineole (XCIII), is one of the chief constituents of eucalyptus and cajepufr oils, and is used medicinally as an antiseptic, antispasmodic, antiperiodic and expectorant. It apparently undergoes oxidation in vivo to hydroxycineole, which is excreted as its glucuronoside (140). The oxidation product may be either 2- or 3-hydroxycineole (XCIV). 

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