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Excipient hydroxypropyl methylcellulose

Excipients Cellulose, disodium hydrogen phosphate, hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose, mannitol, sodium lauryl sulfate, etc. [Pg.162]

Formuiation The formulation consists of excipients such as carnauba wax, crospovidone, hydroxylpropyl cellulose, hydroxypropyl methylcellulose, lactose, magnesium stearate, microcrystalline cellulose, and other inactive ingredients. [Pg.170]

Pantoprazole sodium was separately mixed in 1 1 ratios with sodium carbonate, mannitol, calcium stearate, colloidal anhydrous silica, povidone K90, crospovidone, and hydroxypropyl methylcellulose. The blends were stored at 40°C and 75% relative humidity, at 50°C and 75% relative humidity, and at 65°C for 30 days. No evidence for instability was noted, indicating that pantoprazole sodium is compatible with these common excipients. [Pg.253]

Levina, M., and Rajabi-Siahboomi, A. R. (2004), The influence of excipients on drug release from hydroxypropyl methylcellulose matrices,/. Pharm. Sci., 93, 2746-2754. [Pg.1218]

A simple foam generation apparatus is used to incorporate air into a conventional water-soluble polymeric excipients binder such as METHOCEL hypromeUose (hydroxypropyl methylcellulose). The resulting foam has a consistency like shaving cream. HypromeUose polymers are ideal candidates for this technology because they are excellent film formers and create exceptionally stable foams. [Pg.403]

Hercules Technical Bulletin. VC-556C. FMC s excipients for pharmaceutical tablets, capsules and suspensions. The use of Klucel Pharm hydroxypropylcellulose to increase the utility of hydroxypropyl methylcellulose in aqueous film coating. [Pg.148]

The key consideration in the analysis of any sustained release dosage form as previously discussed (see Sections II.A, II.B, II.C.l, and II.C.2rg) is to determine what solvent or solvent system will be most appropriate to assure the dissolution of the drug and its excipients to make it amenable to HPLC analysis. Aqueous solubility of weak acids and bases is governed by the pfCa of the compound and the pFI of the medium. In an acidic or low pFI medium, weak acids will be unionized and will be more soluble in organic solvents. The reverse is the case for basic compounds as previously discussed in Section II.B. Because the formulation of sustained release dosage forms tend to rely on the use of insoluble plastics (i.e., methyl acrylate-methyl methacrylate, polyvinyl chloride, and polyethylene), hydrophilic polymers (i.e., methylcellulose, hydroxypropyl-methylcellulose, sodium carboxymethyl cellulose, and carbopol 934), and fatty compounds (i.e., waxes such carnauba wax and glyceryl tristearate), similar hydro-organic solvents and sample preparation steps that have been discussed for tablets and capsules can also used for their analysis by HPLC (see Sections II.A, II.B, II.C.l, and II.C.2). [Pg.241]

A variety of polymers are employed as hydrophilic matrix-forming excipients whose characteristics may play a key role and significantly influence the behavior of these devices. Cellulose ethers, especially hydroxypropyl methylcellulose (HPMC), are frequently used as the basis for preparing hydrophilic matrix tablets. [Pg.107]


See other pages where Excipient hydroxypropyl methylcellulose is mentioned: [Pg.424]    [Pg.284]    [Pg.454]    [Pg.2571]    [Pg.4106]    [Pg.222]    [Pg.32]    [Pg.66]    [Pg.5230]    [Pg.491]    [Pg.496]    [Pg.326]    [Pg.143]    [Pg.57]   
See also in sourсe #XX -- [ Pg.765 ]




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